Gene Page: APLP1

Summary
GeneID  333
Symbol  APLP1
Synonyms  APLP
Description  amyloid beta (A4) precursor-like protein 1
See related  HGNC:597|MIM:104775|Ensembl:ENSG00000105290|HPRD:00102|
Locus tag  -
Gene type  protein-coding
Map location  19q13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0625 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005507copper ion bindingIEA-
GO:0005515protein bindingIPI14563850 |16169070 
GO:0008201heparin bindingIEA-
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030900forebrain developmentIEABrain (GO term level: 8)-
GO:0007399nervous system developmentTASneurite (GO term level: 5)9521588 
GO:0006378mRNA polyadenylationIEA-
GO:0006417regulation of translationIEA-
GO:0007155cell adhesionIEA-
GO:0008219cell deathIEA-
GO:0009887organ morphogenesisTAS9521588 
GO:0006915apoptosisIEA-
GO:0006897endocytosisIEA-
GO:0030198extracellular matrix organizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005604basement membraneTAS9521588 
GO:0005624membrane fractionIEA-
GO:0005737cytoplasmIEA-
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APBB1FE65 | MGC:9072 | RIRamyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)-HPRD8894693 
Reconstituted ComplexBioGRID10081969 
APBB3FE65L2 | MGC150555 | MGC87674 | SRAamyloid beta (A4) precursor protein-binding, family B, member 3Reconstituted ComplexBioGRID10081969 
CDKN2CINK4C | p18 | p18-INK4Ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)Two-hybridBioGRID16169070 
CRCT1C1orf42 | NICE-1cysteine-rich C-terminal 1Two-hybridBioGRID16169070 
DAB1-disabled homolog 1 (Drosophila)-HPRD,BioGRID10460257 
DAB2DOC-2 | DOC2 | FLJ26626disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)Reconstituted ComplexBioGRID11247302 
EIF2S2DKFZp686L18198 | EIF2 | EIF2B | EIF2beta | MGC8508eukaryotic translation initiation factor 2, subunit 2 beta, 38kDaTwo-hybridBioGRID16169070 
GSTM4GSTM4-4 | GTM4 | MGC131945 | MGC9247glutathione S-transferase mu 4Two-hybridBioGRID16169070 
HLA-DQA1CD | CELIAC1 | DQ-A1 | FLJ27088 | FLJ27328 | GSE | HLA-DQA | MGC149527major histocompatibility complex, class II, DQ alpha 1Two-hybridBioGRID16169070 
HSPE1CPN10 | GROES | HSP10heat shock 10kDa protein 1 (chaperonin 10)Two-hybridBioGRID16169070 
MPHOSPH6MPP | MPP-6 | MPP6M-phase phosphoprotein 6Two-hybridBioGRID16169070 
NACAHSD48 | MGC117224 | NACA1nascent polypeptide-associated complex alpha subunitTwo-hybridBioGRID16169070 
NPFLJ94043 | FLJ97288 | FLJ97312 | MGC117396 | MGC125915 | MGC125916 | PNP | PRO1837 | PUNPnucleoside phosphorylaseTwo-hybridBioGRID16169070 
PCDHA4CNR1 | CNRN1 | CRNR1 | MGC138307 | MGC142169 | PCDH-ALPHA4protocadherin alpha 4Two-hybridBioGRID16169070 
PHF10FLJ10975 | MGC111009 | XAP135PHD finger protein 10Two-hybridBioGRID16169070 
SAT1DC21 | KFSD | SAT | SSAT | SSAT-1spermidine/spermine N1-acetyltransferase 1Two-hybridBioGRID16169070 
STX5SED5 | STX5Asyntaxin 5Two-hybridBioGRID16169070 
TCF21POD1 | bHLHa23transcription factor 21Two-hybridBioGRID16169070 
TK1TK2thymidine kinase 1, solubleTwo-hybridBioGRID16169070 
TOE1FLJ13949target of EGR1, member 1 (nuclear)Two-hybridBioGRID16169070 
TSC22D1DKFZp686O19206 | MGC17597 | RP11-269C23.2 | TGFB1I4 | TSC22TSC22 domain family, member 1Two-hybridBioGRID16169070 
UTP14AKIAA0266 | NY-CO-16 | SDCCAG16 | dJ537K23.3UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)Two-hybridBioGRID16169070 
ZNF24KOX17 | RSG-A | ZNF191 | ZSCAN3 | Zfp191zinc finger protein 24Two-hybridBioGRID16169070 
 


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