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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: HTR1D

Summary

GeneID

3352

Symbol

HTR1D

Synonyms

5-HT1D|HT1DA|HTR1DA|HTRL|RDC4

Description

5-hydroxytryptamine (serotonin) receptor 1D

Locus tag

Gene type

protein-coding

Map location

1p36.3-p34.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 2

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004993

serotonin receptor activity

TAS

serotonin, Neurotransmitter (GO term level: 8)

1565658

GO:0004872

receptor activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007268

synaptic transmission

TAS

neuron, Synap, Neurotransmitter (GO term level: 6)

1565658

GO:0007187

G-protein signaling, coupled to cyclic nucleotide second messenger

TAS

1565658

GO:0007165

signal transduction

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005886

plasma membrane

IEA

GO:0005887

integral to plasma membrane

TAS

1652050

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
HTR1A	5-HT1A \| 5HT1a \| ADRB2RL1 \| ADRBRL1	5-hydroxytryptamine (serotonin) receptor 1A	-	HPRD,BioGRID	11854302
HTR1A	5-HT1A \| 5HT1a \| ADRB2RL1 \| ADRBRL1	5-hydroxytryptamine (serotonin) receptor 1A	5-HT1A interacts with 5-HT1D. This interaction was modeled on a demonstrated interaction between 5-HT1A and 5-HT1D from an unspecified species.	BIND	11854302
HTR1B	5-HT1B \| 5-HT1DB \| HTR1D2 \| HTR1DB \| S12	5-hydroxytryptamine (serotonin) receptor 1B	-	HPRD,BioGRID	11854302
HTR1B	5-HT1B \| 5-HT1DB \| HTR1D2 \| HTR1DB \| S12	5-hydroxytryptamine (serotonin) receptor 1B	5-HT1D interacts with 5-HT1B. This interaction was modeled on a demonstrated interaction between 5-HT1D and 5-HT1B from an unspecified species.	BIND	11854302
HTR1D	5-HT1D \| HT1DA \| HTR1DA \| HTRL \| RDC4	5-hydroxytryptamine (serotonin) receptor 1D	-	HPRD	11854302
HTR1D	5-HT1D \| HT1DA \| HTR1DA \| HTRL \| RDC4	5-hydroxytryptamine (serotonin) receptor 1D	5-HT1D homodimerizes. This interaction was modeled on a demonstrated interaction between two 5-HT1D from an unspecified species.	BIND	11854302
S1PR1	CHEDG1 \| D1S3362 \| ECGF1 \| EDG-1 \| EDG1 \| FLJ58121 \| S1P1	sphingosine-1-phosphate receptor 1	5-HT1D interacts with EDG1. This interaction was modeled on a demonstrated interaction between 5-HT1D and EDG1 from an unspecified species.	BIND	11854302
S1PR1	CHEDG1 \| D1S3362 \| ECGF1 \| EDG-1 \| EDG1 \| FLJ58121 \| S1P1	sphingosine-1-phosphate receptor 1	-	HPRD,BioGRID	11854302

Pathway annotation

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-379	657	663	m8	hsa-miR-379^brain	UGGUAGACUAUGGAACGUA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.