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GeneID |
3356
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Symbol |
HTR2A
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Synonyms |
5-HT2A|HTR2
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Description |
5-hydroxytryptamine (serotonin) receptor 2A |
See related |
HGNC:5293|MIM:182135|Ensembl:ENSG00000102468|HPRD:01638| |
Locus tag |
RP11-147L20.2 |
Gene type |
protein-coding |
Map location |
13q14-q21 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Association | A combined odds ratio method (Sun et al. 2008), association studies | 3 | Link to SZGene | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias, schizophrenic] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 3 | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 31 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
LRPPRC | 0.94 | 0.95 | | |
ELP3 | 0.93 | 0.92 | | |
NPEPPS | 0.93 | 0.93 | | |
EIF2AK1 | 0.93 | 0.95 | | |
KIAA1012 | 0.93 | 0.93 | | |
PPME1 | 0.93 | 0.92 | | |
ARMC8 | 0.93 | 0.93 | | |
KPNA4 | 0.93 | 0.94 | | |
RBBP5 | 0.93 | 0.93 | | |
CUL2 | 0.93 | 0.92 | | |
Top 10 negatively co-expressed genes | AF347015.31 | -0.78 | -0.77 | | |
MT-CO2 | -0.77 | -0.77 | | |
AF347015.8 | -0.76 | -0.76 | | |
AF347015.21 | -0.75 | -0.75 | | |
AF347015.2 | -0.75 | -0.74 | | |
AF347015.33 | -0.74 | -0.74 | | |
HIGD1B | -0.74 | -0.75 | | |
MT-CYB | -0.74 | -0.74 | | |
FXYD1 | -0.74 | -0.76 | | |
AF347015.27 | -0.73 | -0.74 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0004993 | serotonin receptor activity | TAS | serotonin, Neurotransmitter (GO term level: 8) | 9109547 |
GO:0004872 | receptor activity | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007268 | synaptic transmission | TAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 9109547 |
GO:0007210 | serotonin receptor signaling pathway | TAS | serotonin (GO term level: 8) | 9109547 |
GO:0007165 | signal transduction | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005886 | plasma membrane | IEA | | - |
GO:0005887 | integral to plasma membrane | TAS | | 9109547 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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