Gene Page: IHH

Summary
GeneID  3549
Symbol  IHH
Synonyms  BDA1|HHG2
Description  Indian hedgehog homolog (Drosophila)
See related  HGNC:5956|MIM:600726|Ensembl:ENSG00000163501|HPRD:02839|
Locus tag  -
Gene type  protein-coding
Map location  2q33-q35
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005113patched bindingNAS-
GO:0005515protein bindingIEA-
GO:0016740transferase activityIEA-
GO:0008233peptidase activityIEA-
GO:0015485cholesterol bindingNAS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001569patterning of blood vesselsIEA-
GO:0001501skeletal system developmentIEA-
GO:0001649osteoblast differentiationIEA-
GO:0006508proteolysisIEA-
GO:0007267cell-cell signalingNAS-
GO:0008284positive regulation of cell proliferationIEA-
GO:0048469cell maturationIEA-
GO:0007389pattern specification processIEA-
GO:0016539intein-mediated protein splicingIEA-
GO:0045596negative regulation of cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionNAS-
GO:0005886plasma membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
PTCH1BCNS | FLJ26746 | FLJ42602 | HPE7 | NBCCS | PTC | PTC1 | PTCH | PTCH11patched homolog 1 (Drosophila)-HPRD9811851 
PTCH2-patched homolog 2 (Drosophila)-HPRD9811851 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_HEDGEHOG_SIGNALING_PATHWAY 5642All SZGR genes in this pathway
PID_HEDGEHOG_2PATHWAY 2217All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS 8858All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP 211136All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
PEREZ_TP53_AND_TP63_TARGETS 205145All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_3 4831All SZGR genes in this pathway
SCHLESINGER_METHYLATED_IN_COLON_CANCER 107All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_NEOCORTEX_DN 8858All SZGR genes in this pathway
FIRESTEIN_PROLIFERATION 175125All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME2_AND_H3K27ME3 5935All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 4936All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP 289184All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
NABA_SECRETED_FACTORS 344197All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-103/107378384m8hsa-miR-103brainAGCAGCAUUGUACAGGGCUAUGA
hsa-miR-107brainAGCAGCAUUGUACAGGGCUAUCA
miR-122503509m8hsa-miR-122aUGGAGUGUGACAAUGGUGUUUGU
miR-15/16/195/424/4973793861A,m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-1507177231Ahsa-miR-150UCUCCCAACCCUUGUACCAGUG
miR-23565571m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-3235655711Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-5033803861Ahsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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