Gene Page: ARF1

Summary
GeneID  375
Symbol  ARF1
Synonyms  -
Description  ADP-ribosylation factor 1
See related  HGNC:652|MIM:103180|Ensembl:ENSG00000143761|HPRD:00054|
Locus tag  -
Gene type  protein-coding
Map location  1q42
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0309 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
COPB10.960.96
CCT6A0.950.95
YWHAQ0.950.95
PAIP10.950.95
MRPL30.950.96
CSE1L0.940.94
PWP10.940.94
MATR30.940.93
ACTR30.940.94
MARCH50.940.92
Top 10 negatively co-expressed genes
MT-CO2-0.75-0.85
AF347015.33-0.75-0.85
AF347015.8-0.74-0.85
AF347015.27-0.73-0.83
AF347015.31-0.73-0.82
MT-CYB-0.73-0.83
AF347015.15-0.72-0.84
HLA-F-0.71-0.78
AF347015.2-0.71-0.84
AF347015.26-0.70-0.83
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005057receptor signaling protein activityTAS8529647 
GO:0003924GTPase activityTAS1577740 
GO:0005515protein bindingIPI9819391 |14654833 |14690595 
GO:0005525GTP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016044membrane organizationEXP11031247 
GO:0007264small GTPase mediated signal transductionIEA-
GO:0006890retrograde vesicle-mediated transport, Golgi to EREXP11031247 
GO:0016192vesicle-mediated transportIEA-
GO:0015031protein transportIEA-
GO:0048205COPI coating of Golgi vesicleEXP16956762 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneEXP8533093 |8599108 |10402461 
GO:0005794Golgi apparatusIEA-
GO:0005829cytosolEXP15202998 
GO:0005829cytosolIEA-
GO:0005622intracellularIEA-
GO:0030017sarcomereIEA-
GO:0005886plasma membraneTAS8529647 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AP1B1ADTB1 | AP105A | BAM22 | CLAPB2adaptor-related protein complex 1, beta 1 subunit-HPRD,BioGRID11926829 
AP1G1ADTG | CLAPG1 | MGC18255adaptor-related protein complex 1, gamma 1 subunit-HPRD,BioGRID11926829 
AP3D1ADTD | hBLVRadaptor-related protein complex 3, delta 1 subunit-HPRD11926829 
AP3S2AP3S3 | FLJ35955 | sigma3badaptor-related protein complex 3, sigma 2 subunitReconstituted ComplexBioGRID11926829 
AP4E1DKFZp686L12167adaptor-related protein complex 4, epsilon 1 subunitReconstituted Complex
Two-hybrid		BioGRID11707398 
AP4M1MU-4 | MU-ARP2adaptor-related protein complex 4, mu 1 subunit-HPRD,BioGRID11707398 
ARF1-ADP-ribosylation factor 1-HPRD,BioGRID7990966 
ARFGAP1ARF1GAP | HRIHFB2281 | MGC39924ADP-ribosylation factor GTPase activating protein 1-HPRD9733781 
ARFIP1HSU52521 | MGC117369ADP-ribosylation factor interacting protein 1-HPRD,BioGRID9038142 
ARFIP2POR1ADP-ribosylation factor interacting protein 2-HPRD,BioGRID9038142 
ASAP2AMAP2 | CENTB3 | DDEF2 | FLJ42910 | KIAA0400 | PAG3 | PAP | Pap-alpha | SHAG1ArfGAP with SH3 domain, ankyrin repeat and PH domain 2-HPRD10022920 |10749932 
C4orf14MGC3232 | hAtNOS1 | mAtNOS1chromosome 4 open reading frame 14Two-hybridBioGRID16169070 
CHRM3HM3cholinergic receptor, muscarinic 3Affinity Capture-Western
Reconstituted Complex		BioGRID12799371 
COPB1COPB | DKFZp761K102 | FLJ10341coatomer protein complex, subunit beta 1-HPRD,BioGRID10720466 
COPEFLJ13241 | epsilon-COPcoatomer protein complex, subunit epsilon-HPRD,BioGRID10921873 
COPGCOPG1 | FLJ21068coatomer protein complex, subunit gammaAffinity Capture-WesternBioGRID10720466 
CYTH1B2-1 | CYTOHESIN-1 | D17S811E | FLJ34050 | FLJ41900 | PSCD1 | SEC7cytohesin 1-HPRD9653114 |9756891 
|10212218 
CYTH2ARNO | CTS18 | CTS18.1 | PSCD2 | PSCD2L | SEC7L | Sec7p-L | Sec7p-likecytohesin 2-HPRD,BioGRID9417041 
EEF1GEF1G | GIG35eukaryotic translation elongation factor 1 gammaTwo-hybridBioGRID16169070 
GGA1-golgi associated, gamma adaptin ear containing, ARF binding protein 1-HPRD10747089 
-HPRD,BioGRID12636914 
GGA2FLJ20966 | KIAA1080 | VEARgolgi associated, gamma adaptin ear containing, ARF binding protein 2-HPRD10747089 
GGA3KIAA0154golgi associated, gamma adaptin ear containing, ARF binding protein 3-HPRD,BioGRID10747089 
KDELR1ERD2 | ERD2.1 | HDEL | PM23KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1-HPRD,BioGRID11703931 
MDM4DKFZp781B1423 | HDMX | MDMX | MGC132766 | MRP1Mdm4 p53 binding protein homolog (mouse)-HPRD11297540 
NPM1B23 | MGC104254 | NPMnucleophosmin (nucleolar phosphoprotein B23, numatrin)-HPRD14636574 |15684379 
OPRM1KIAA0403 | MOR | MOR1 | OPRMopioid receptor, mu 1Affinity Capture-WesternBioGRID12519790 
PIP5K1A-phosphatidylinositol-4-phosphate 5-kinase, type I, alpha-HPRD10589680 |10747863 
PLD1-phospholipase D1, phosphatidylcholine-specific-HPRD,BioGRID9688545 
PLD2-phospholipase D2Reconstituted ComplexBioGRID10801846 |11373276 
-HPRD10801846 |12519790 
PLEKHA8FAPP2 | MGC3358pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8-HPRD15107860 
RALAMGC48949 | RALv-ral simian leukemia viral oncogene homolog A (ras related)Reconstituted ComplexBioGRID9688545 
-HPRD12509462 
STAU1FLJ25010 | STAUstaufen, RNA binding protein, homolog 1 (Drosophila)Stau1 interacts with Arf1.BIND15680326 
TMED10P24(DELTA) | S31I125 | S31III125 | TMP21 | Tmp-21-Itransmembrane emp24-like trafficking protein 10 (yeast)-HPRD11726511 
TMED2FLJ21323 | P24A | RNP24transmembrane emp24 domain trafficking protein 2-HPRD11703931 
WBP11DKFZp779M1063 | NPWBP | SIPP1WW domain binding protein 11Two-hybridBioGRID16169070 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1388428491A,m8hsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-1532132201A,m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-25/32/92/363/3672162221Ahsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-264404461Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-3708458521A,m8hsa-miR-370brainGCCUGCUGGGGUGGAACCUGG
miR-381111811241Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-4482142201Ahsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-4961701761Ahsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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