Gene Page: KRT18

Summary
GeneID  3875
Symbol  KRT18
Synonyms  CYK18|K18
Description  keratin 18
See related  HGNC:6430|MIM:148070|Ensembl:ENSG00000111057|HPRD:01020|
Locus tag  -
Gene type  protein-coding
Map location  12q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0344 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10954706 |11684708 
GO:0005198structural molecule activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0043000Golgi to plasma membrane CFTR protein transportIDA15529338 
GO:0007049cell cycleIEA-
GO:0009653anatomical structure morphogenesisTAS2434380 
GO:0043066negative regulation of apoptosisIDA11684708 
GO:0033209tumor necrosis factor-mediated signaling pathwayIEA-
GO:0044419interspecies interaction between organismsIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005815microtubule organizing centerIDA18000879 
GO:0005737cytoplasmIDA16424149 
GO:0034451centriolar satelliteIDA18000879 
GO:0045095keratin filamentIDA16424149 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CBLC-CBL | CBL2 | RNF55Cas-Br-M (murine) ecotropic retroviral transforming sequencec-Cbl interacts with Keratin 18.BIND9367879 
-HPRD,BioGRID9367879 
CCDC85BDIPAcoiled-coil domain containing 85BTwo-hybridBioGRID16189514 
CLEC3BDKFZp686H17246 | TN | TNAC-type lectin domain family 3, member BAffinity Capture-MSBioGRID17353931 
COL17A1BA16H23.2 | BP180 | BPAG2 | FLJ60881 | KIAA0204 | LAD-1collagen, type XVII, alpha 1-HPRD,BioGRID10022517 
DEDDCASP8IP1 | DEDD1 | DEFT | FLDED1 | KE05death effector domain containing-HPRD,BioGRID12235123 
DNAJB6DJ4 | DKFZp566D0824 | DnaJ | FLJ42837 | HHDJ1 | HSJ-2 | HSJ2 | MGC1152 | MGC117297 | MRJ | MSJ-1DnaJ (Hsp40) homolog, subfamily B, member 6-HPRD,BioGRID10954706 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)-HPRD12577067 
EXOC8EXO84 | Exo84p | SEC84exocyst complex component 8Two-hybridBioGRID16189514 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2Affinity Capture-MSBioGRID12577067 
HGSHRS | ZFYVE8hepatocyte growth factor-regulated tyrosine kinase substrateTwo-hybridBioGRID16189514 
HSPA4APG-2 | HS24/P52 | MGC131852 | RY | hsp70 | hsp70RYheat shock 70kDa protein 4Reconstituted ComplexBioGRID7529764 
HSPA5BIP | FLJ26106 | GRP78 | MIF2heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)-HPRD9409741 
KRT15CK15 | K15 | K1COkeratin 15Two-hybridBioGRID16189514 
KRT5CK5 | DDD | EBS2 | K5 | KRT5Akeratin 5-HPRD,BioGRID9786957 
KRT8CARD2 | CK8 | CYK8 | K2C8 | K8 | KOkeratin 8-HPRD,BioGRID9630597 
LDOC1BCUR1 | Mar7 | Mart7leucine zipper, down-regulated in cancer 1Two-hybridBioGRID16189514 
MAPK14CSBP1 | CSBP2 | CSPB1 | EXIP | Mxi2 | PRKM14 | PRKM15 | RK | SAPK2A | p38 | p38ALPHAmitogen-activated protein kinase 14-HPRD,BioGRID11788583 
MCCDKFZp762O1615 | FLJ38893 | FLJ46755 | MCC1mutated in colorectal cancersAffinity Capture-MSBioGRID17353931 
NME7FLJ37194 | nm23-H7non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)Two-hybridBioGRID16189514 
PKD1PBPpolycystic kidney disease 1 (autosomal dominant)-HPRD,BioGRID11581269 
PKP2ARVD9plakophilin 2-HPRD,BioGRID10852826 
PKP3-plakophilin 3Two-hybridBioGRID12707304 
PKP3 interacts with KRT18 (CK18)BIND12707304 
PNNDRS | SDK3 | memA | pininpinin, desmosome associated protein-HPRD,BioGRID10809736 
PPM1BMGC21657 | PP2C-beta-X | PP2CB | PP2CBETA | PPC2BETAXprotein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoformAffinity Capture-MSBioGRID17353931 
PRKCEMGC125656 | MGC125657 | PKCE | nPKC-epsilonprotein kinase C, epsilon-HPRD,BioGRID1374067 
RHPN2RhoBP | p76RBErhophilin, Rho GTPase binding protein 2-HPRD12473120 
SFNYWHASstratifin-HPRD11917136 
TNFRSF1BCD120b | TBPII | TNF-R-II | TNF-R75 | TNFBR | TNFR1B | TNFR2 | TNFR80 | p75 | p75TNFRtumor necrosis factor receptor superfamily, member 1B-HPRD,BioGRID10747083 
TRADDHs.89862 | MGC11078TNFRSF1A-associated via death domainK18 interacts with TRADD.BIND11684708 
-HPRD,BioGRID11684708 
TUBGCP476P | FLJ14797 | GCP4tubulin, gamma complex associated protein 4Two-hybridBioGRID16189514 
USH2ARP39 | US2 | USH2 | USHERIN | dJ1111A8.1Usher syndrome 2A (autosomal recessive, mild)-HPRD,BioGRID276901 
YWHABGW128 | HS1 | KCIP-1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide-HPRD9524113 
YWHAE14-3-3E | FLJ45465 | KCIP-1 | MDCR | MDStyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide-HPRD9524113 
YWHAG14-3-3GAMMAtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide-HPRD9524113 
YWHAHYWHA1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide-HPRD9524113 
YWHAQ14-3-3 | 1C5 | HS1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptideAffinity Capture-WesternBioGRID9524113 
YWHAZKCIP-1 | MGC111427 | MGC126532 | MGC138156tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide-HPRD9524113 |11917136 
 


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