Gene Page: LAMC1

Summary
GeneID  3915
Symbol  LAMC1
Synonyms  LAMB2|MGC87297
Description  laminin, gamma 1 (formerly LAMB2)
See related  HGNC:6492|MIM:150290|Ensembl:ENSG00000135862|HPRD:01030|
Locus tag  RP11-181K3.1
Gene type  protein-coding
Map location  1q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.02 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0005201extracellular matrix structural constituentIMP15159456 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionIDA15159456 
GO:0006461protein complex assemblyIDA15159456 
GO:0022617extracellular matrix disassemblyIMP15159456 
GO:0007492endoderm developmentTAS9885251 
GO:0016477cell migrationIMP15561105 
GO:0031581hemidesmosome assemblyIMP15159456 
GO:0050679positive regulation of epithelial cell proliferationTAS14557481 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005605basal laminaIEA-
GO:0005606laminin-1 complexTAS14557481 
GO:0005737cytoplasmIDA18029348 
GO:0005783endoplasmic reticulumIDA18029348 
GO:0005886plasma membraneIDA18029348 
GO:0043259laminin-10 complexIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CCDC53CGI-116coiled-coil domain containing 53Two-hybridBioGRID16169070 
LAMA5KIAA1907laminin, alpha 5-HPRD11133776 
NID1NIDnidogen 1-HPRD,BioGRID9733643 
NID2-nidogen 2 (osteonidogen)-HPRD,BioGRID9733643 
SNAPINSNAPAPSNAP-associated proteinTwo-hybridBioGRID16169070 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-12224902496m8hsa-miR-122aUGGAGUGUGACAAUGGUGUUUGU
miR-124.1268126881A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/506268126871Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-15/16/195/424/497103109m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-153139714041A,m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-1825265321Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-19914591465m8hsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
miR-200bc/42927592765m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-2054004071A,m8hsa-miR-205UCCUUCAUUCCACCGGAGUCUG
miR-21613721378m8hsa-miR-216UAAUCUCAGCUGGCAACUGUG
miR-22718724m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-29146314701A,m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-3751831891Ahsa-miR-375UUUGUUCGUUCGGCUCGCGUGA
miR-3763974041A,m8hsa-miR-376aAUCAUAGAGGAAAAUCCACGU
hsa-miR-376bAUCAUAGAGGAAAAUCCAUGUU
miR-377149515021A,m8hsa-miR-377AUCACACAAAGGCAACUUUUGU
miR-384687693m8hsa-miR-384AUUCCUAGAAAUUGUUCAUA
miR-433-3p15201526m8hsa-miR-433brainAUCAUGAUGGGCUCCUCGGUGU
miR-448139814041Ahsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-496154515511Ahsa-miR-496AUUACAUGGCCAAUCUC
miR-965255321A,m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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