Gene Page: LPA

Summary
GeneID  4018
Symbol  LPA
Synonyms  AK38|APOA|LP
Description  lipoprotein, Lp(a)
See related  HGNC:6667|MIM:152200|Ensembl:ENSG00000198670|HPRD:01063|
Locus tag  -
Gene type  protein-coding
Map location  6q26
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PDE1B0.870.88
RAP1GAP0.860.84
HPCA0.840.79
RASD20.840.85
ADRA2C0.840.69
TESC0.830.75
AC005512.10.830.64
LINGO30.820.73
RGS140.820.81
KCNAB10.820.79
Top 10 negatively co-expressed genes
AC132872.1-0.35-0.46
KCNMB3-0.33-0.36
KIAA1949-0.32-0.26
RBMX2-0.31-0.44
ZNF300-0.31-0.15
AC005921.3-0.31-0.52
ZNF311-0.31-0.22
TUBB2B-0.31-0.35
AC005768.1-0.30-0.33
SH3BP2-0.30-0.40
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0005509calcium ion bindingIEA-
GO:0004866endopeptidase inhibitor activityTAS8047165 
GO:0008233peptidase activityIEA-
GO:0034185apolipoprotein bindingIPI9269765 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0008015blood circulationTAS8047165 
GO:0007596blood coagulationIEA-
GO:0006629lipid metabolic processNAS8047165 
GO:0006869lipid transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP9548923 
GO:0005576extracellular regionNAS14718574 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CANXCNX | FLJ26570 | IP90 | P90calnexin-HPRD,BioGRID9717723 |12562843 
FBLN5ARMD3 | DANCE | EVEC | FIBL-5 | FLJ90059 | UP50fibulin 5-HPRD12111551 
FGBMGC104327 | MGC120405fibrinogen beta chain-HPRD,BioGRID10980194 
FN1CIG | DKFZp686F10164 | DKFZp686H0342 | DKFZp686I1370 | DKFZp686O13149 | ED-B | FINC | FN | FNZ | GFND | GFND2 | LETS | MSFfibronectin 1-HPRD,BioGRID2531657 
LRP2DBS | gp330low density lipoprotein-related protein 2-HPRD,BioGRID10073957 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ST_GA13_PATHWAY 3732All SZGR genes in this pathway
PID_AMB2_NEUTROPHILS_PATHWAY 4132All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT 4637All SZGR genes in this pathway
REACTOME_LIPOPROTEIN_METABOLISM 2824All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
SU_LIVER 5532All SZGR genes in this pathway
LEE_LIVER_CANCER 4929All SZGR genes in this pathway
CAMPS_COLON_CANCER_COPY_NUMBER_DN 7434All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP 8550All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
NABA_ECM_REGULATORS 238125All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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