ACVR1B | ACTRIB | ACVRLK4 | ALK4 | SKR2 | activin A receptor, type IB | Affinity Capture-Western | BioGRID | 9892009 |
AKT1 | AKT | MGC99656 | PKB | PKB-ALPHA | PRKBA | RAC | RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 | Affinity Capture-Western | BioGRID | 16362038 |
ANAPC10 | APC10 | DKFZp564L0562 | DOC1 | anaphase promoting complex subunit 10 | Affinity Capture-Western Reconstituted Complex | BioGRID | 15144564 |
Smad3 interacts with APC10. | BIND | 15144564 |
AR | AIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFM | androgen receptor | - | HPRD,BioGRID | 11280774 |
ATF2 | CRE-BP1 | CREB2 | HB16 | MGC111558 | TREB7 | activating transcription factor 2 | - | HPRD,BioGRID | 10085140 |
ATF3 | - | activating transcription factor 3 | - | HPRD,BioGRID | 12718878 |
AXIN1 | AXIN | MGC52315 | axin 1 | - | HPRD | 11438668 |
BRCA1 | BRCAI | BRCC1 | IRIS | PSCP | RNF53 | breast cancer 1, early onset | BRCA1 interacts with Smad3. | BIND | 15735739 |
BRCA2 | BRCC2 | FACD | FAD | FAD1 | FANCB | FANCD | FANCD1 | breast cancer 2, early onset | SMAD3 interacts with BRCA2. | BIND | 12165866 |
- | HPRD,BioGRID | 12165866 |
BTRC | BETA-TRCP | FBW1A | FBXW1 | FBXW1A | FWD1 | MGC4643 | bTrCP | bTrCP1 | betaTrCP | beta-transducin repeat containing | Affinity Capture-Western | BioGRID | 14988407 |
CAMK2G | CAMK | CAMK-II | CAMKG | FLJ16043 | MGC26678 | calcium/calmodulin-dependent protein kinase II gamma | - | HPRD | 11027280 |
CDC16 | APC6 | cell division cycle 16 homolog (S. cerevisiae) | - | HPRD,BioGRID | 11691834 |
CDC27 | APC3 | CDC27Hs | D0S1430E | D17S978E | HNUC | cell division cycle 27 homolog (S. cerevisiae) | - | HPRD,BioGRID | 11691834 |
CDK2 | p33(CDK2) | cyclin-dependent kinase 2 | CDK2 phosphorylates Smad3 on Thr8, Thr179, Ser204, Ser208 and Ser213. This interaction was modelled on a demonstrated interaction between Smad3 from an unspecified species and human CDK2. | BIND | 15241418 |
CDK4 | CMM3 | MGC14458 | PSK-J3 | cyclin-dependent kinase 4 | CDK4 phosphorylates Smad3 on Thr8, Thr179, Ser204, Ser208 and Ser213. This interaction was modelled on a demonstrated interaction between Smad3 from an unspecified species and mouse CDK4. | BIND | 15241418 |
CEBPA | C/EBP-alpha | CEBP | CCAAT/enhancer binding protein (C/EBP), alpha | Reconstituted Complex | BioGRID | 12524424 |
CEBPB | C/EBP-beta | CRP2 | IL6DBP | LAP | MGC32080 | NF-IL6 | TCF5 | CCAAT/enhancer binding protein (C/EBP), beta | - | HPRD,BioGRID | 12524424 |
CEBPD | C/EBP-delta | CELF | CRP3 | NF-IL6-beta | CCAAT/enhancer binding protein (C/EBP), delta | Affinity Capture-Western Reconstituted Complex | BioGRID | 12524424 |
CREBBP | CBP | KAT3A | RSTS | CREB binding protein | CBP interacts with Smad3. This interaction was modeled on a demonstrated interaction between mouse CBP and Smad3 from an unspecified species. | BIND | 15750622 |
CTNNB1 | CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923 | catenin (cadherin-associated protein), beta 1, 88kDa | - | HPRD,BioGRID | 12000714 |
DAB2 | DOC-2 | DOC2 | FLJ26626 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | - | HPRD,BioGRID | 11387212 |
DACH1 | DACH | FLJ10138 | dachshund homolog 1 (Drosophila) | - | HPRD | 14525983 |
DVL1 | DVL | MGC54245 | dishevelled, dsh homolog 1 (Drosophila) | Reconstituted Complex Two-hybrid | BioGRID | 12650946 |
E2F4 | E2F-4 | E2F transcription factor 4, p107/p130-binding | - | HPRD,BioGRID | 12150994 |
EID2 | CRI2 | EID-2 | MGC20452 | EP300 interacting inhibitor of differentiation 2 | - | HPRD,BioGRID | 14612439 |
EIF4ENIF1 | 4E-T | Clast4 | FLJ21601 | FLJ26551 | eukaryotic translation initiation factor 4E nuclear import factor 1 | Smad3 interacts with 4-ET. This interaction was modeled on a demonstrated interaction between human Smad3 and mouse 4-ET. | BIND | 14651998 |
EP300 | KAT3B | p300 | E1A binding protein p300 | Smad3 interacts with p300. This interaction was modeled on a demonstrated interaction between Smad3 and p300 from an unspecified sources. | BIND | 10497242 |
SMAD3 interacts with EP300 (p300). | BIND | 15688032 |
ERBB2IP | ERBIN | LAP2 | erbb2 interacting protein | - | HPRD,BioGRID | 12650946 |
EVI1 | AML1-EVI-1 | EVI-1 | MDS1-EVI1 | MGC163392 | PRDM3 | ecotropic viral integration site 1 | - | HPRD,BioGRID | 9665135 |
FOS | AP-1 | C-FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | Reconstituted Complex Two-hybrid | BioGRID | 9732876 |
FOXH1 | FAST-1 | FAST1 | forkhead box H1 | The SIM motif of FoxH1 interacts with Smad3. This interaction was modeled on a demonstrated interaction between human FoxH1 and Smad3 from an unspecified species. | BIND | 15750622 |
FoxH1 interacts with Smad3. This interaction was modelled on a demonstrated interaction between FoxH1 from an unspecified species and Smad3 from an unspecified species. | BIND | 15084259 |
- | HPRD,BioGRID | 9858566 |
FOXO1 | FKH1 | FKHR | FOXO1A | forkhead box O1 | FoxO1 interacts with Smad3. This interaction was modelled on a demonstrated interaction between FoxO1 from an unspecified species and Smad3 from an unspecified species. | BIND | 15084259 |
- | HPRD,BioGRID | 15084259 |
FOXO3 | AF6q21 | DKFZp781A0677 | FKHRL1 | FKHRL1P2 | FOXO2 | FOXO3A | MGC12739 | MGC31925 | forkhead box O3 | FoxO3 interacts with Smad3. | BIND | 15084259 |
- | HPRD,BioGRID | 15084259 |
FOXO4 | AFX | AFX1 | MGC120490 | MLLT7 | forkhead box O4 | FoxO4 interacts with Smad3. This interaction was modelled on a demonstrated interaction between FoxO4 from human and Smad3 from an unspecified species. | BIND | 15084259 |
- | HPRD,BioGRID | 15084259 |
GLI3 | ACLS | GCPS | PAP-A | PAPA | PAPA1 | PAPB | PHS | PPDIV | GLI-Kruppel family member GLI3 | - | HPRD | 9843199 |
HIPK2 | DKFZp686K02111 | FLJ23711 | PRO0593 | homeodomain interacting protein kinase 2 | Reconstituted Complex | BioGRID | 12874272 |
JUN | AP-1 | AP1 | c-Jun | jun oncogene | - | HPRD,BioGRID | 9732876 |
JUNB | AP-1 | jun B proto-oncogene | - | HPRD | 10903323 |
Reconstituted Complex Two-hybrid | BioGRID | 10220381 |
JUND | AP-1 | jun D proto-oncogene | Reconstituted Complex | BioGRID | 10220381 |
KPNB1 | IMB1 | IPOB | Impnb | MGC2155 | MGC2156 | MGC2157 | NTF97 | karyopherin (importin) beta 1 | - | HPRD,BioGRID | 10846168 |
LEF1 | DKFZp586H0919 | TCF1ALPHA | lymphoid enhancer-binding factor 1 | Lef1 interacts with Smad3. This interaction was modeled on a demonstrated interaction between mouse Lef1 and Smad3 from an unspecified species. | BIND | 15750622 |
- | HPRD,BioGRID | 10890911 |
MAGI2 | ACVRIP1 | AIP1 | ARIP1 | MAGI-2 | SSCAM | membrane associated guanylate kinase, WW and PDZ domain containing 2 | - | HPRD | 10681527 |
MAPK8 | JNK | JNK1 | JNK1A2 | JNK21B1/2 | PRKM8 | SAPK1 | mitogen-activated protein kinase 8 | - | HPRD | 10601313 |
MAX | MGC10775 | MGC11225 | MGC18164 | MGC34679 | MGC36767 | bHLHd4 | orf1 | MYC associated factor X | - | HPRD,BioGRID | 12551947 |
MDM4 | DKFZp781B1423 | HDMX | MDMX | MGC132766 | MRP1 | Mdm4 p53 binding protein homolog (mouse) | - | HPRD,BioGRID | 12483531 |
MED15 | ARC105 | CAG7A | CTG7A | DKFZp686A2214 | DKFZp762B1216 | FLJ42282 | FLJ42935 | PCQAP | TIG-1 | TIG1 | TNRC7 | mediator complex subunit 15 | - | HPRD | 12167862 |
MEN1 | MEAI | SCG2 | multiple endocrine neoplasia I | - | HPRD,BioGRID | 11274402 |
MYC | bHLHe39 | c-Myc | v-myc myelocytomatosis viral oncogene homolog (avian) | - | HPRD,BioGRID | 11804592 |
NEDD9 | CAS-L | CAS2 | CASL | CASS2 | HEF1 | dJ49G10.2 | dJ761I2.1 | neural precursor cell expressed, developmentally down-regulated 9 | Smad3 interacts with HEF1. | BIND | 15144564 |
- | HPRD,BioGRID | 11118211 |15051726 |15144564 |
NFYC | CBF-C | CBFC | DKFZp667G242 | FLJ45775 | H1TF2A | HAP5 | HSM | NF-YC | nuclear transcription factor Y, gamma | - | HPRD,BioGRID | 12023901 |
NOTCH1 | TAN1 | hN1 | Notch homolog 1, translocation-associated (Drosophila) | - | HPRD,BioGRID | 14638857 |
NR3C1 | GCCR | GCR | GR | GRL | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | - | HPRD,BioGRID | 10518526 |12902338
|
NUP214 | CAIN | CAN | D9S46E | MGC104525 | N214 | nucleoporin 214kDa | Smad3 interacts with CAN/Nup214. This interaction was modelled on a demonstrated interaction between Smad3 and CAN/Nup214 whose origins are unknown. | BIND | 12917407 |
PARD3B | ALS2CR19 | MGC16131 | PAR3B | PAR3L | PAR3LC | PAR3beta | Par3Lb | par-3 partitioning defective 3 homolog B (C. elegans) | Reconstituted Complex Two-hybrid | BioGRID | 12650946 |
PEX6 | PAF-2 | PAF2 | PXAAA1 | peroxisomal biogenesis factor 6 | Smad3 interacts with Pex6. This interaction is modeled on demonstrated interaction between human Smad3 and mouse Pex6. | BIND | 14651998 |
PIAS3 | FLJ14651 | ZMIZ5 | protein inhibitor of activated STAT, 3 | - | HPRD,BioGRID | 14691252 |
PIAS4 | FLJ12419 | MGC35296 | PIASY | Piasg | ZMIZ6 | protein inhibitor of activated STAT, 4 | Affinity Capture-Western | BioGRID | 12815042 |
PML | MYL | PP8675 | RNF71 | TRIM19 | promyelocytic leukemia | cPML interacts with Smad3. | BIND | 15356634 |
- | HPRD,BioGRID | 15356634 |
RBL1 | CP107 | MGC40006 | PRB1 | p107 | retinoblastoma-like 1 (p107) | - | HPRD,BioGRID | 12150994 |
RNF111 | ARK | DKFZp313E0731 | DKFZp686H1966 | DKFZp761D081 | FLJ38008 | ring finger protein 111 | - | HPRD,BioGRID | 14657019 |
RUNX1 | AML1 | AML1-EVI-1 | AMLCR1 | CBFA2 | EVI-1 | PEBP2aB | runt-related transcription factor 1 | Affinity Capture-Western | BioGRID | 10531362 |
RUNX2 | AML3 | CBFA1 | CCD | CCD1 | MGC120022 | MGC120023 | OSF2 | PEA2aA | PEBP2A1 | PEBP2A2 | PEBP2aA | PEBP2aA1 | runt-related transcription factor 2 | - | HPRD,BioGRID | 10962029 |
RUNX3 | AML2 | CBFA3 | FLJ34510 | MGC16070 | PEBP2aC | runt-related transcription factor 3 | - | HPRD | 15138260 |
Affinity Capture-Western | BioGRID | 10531362 |
SF3B2 | SAP145 | SF3B145 | SF3b1 | SF3b150 | splicing factor 3b, subunit 2, 145kDa | Smad3 interacts with SF3b2. This interaction is modeled on demonstrated interaction between human Smad3 and mouse SF3b2. | BIND | 14651998 |
SKI | SKV | v-ski sarcoma viral oncogene homolog (avian) | - | HPRD,BioGRID | 12857746 |
c-Ski interacts with Smad3. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified source and human c-Ski. | BIND | 10575014 |
SKIL | SNO | SnoA | SnoN | SKI-like oncogene | Smad3 interacts with SnoN. This interaction was modeled on a demonstrated interaction between SnoN from an unspecified source and human Smad3. | BIND | 12426322 |
- | HPRD,BioGRID | 10531062 |
SMAD2 | JV18 | JV18-1 | MADH2 | MADR2 | MGC22139 | MGC34440 | hMAD-2 | hSMAD2 | SMAD family member 2 | Smad2 interacts with Smad3. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad3 from an unspecified species. | BIND | 9311995 |
SMAD3 interacts with SMAD2. | BIND | 15761153 |
- | HPRD,BioGRID | 9311995 |
SMAD4 | DPC4 | JIP | MADH4 | SMAD family member 4 | - | HPRD | 9311995|9732876 |
Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species. | BIND | 9311995 |
Smad4 interacts with Smad3. | BIND | 15761153 |
Affinity Capture-Western | BioGRID | 9311995 |9892009 |10531362 |11114293 |12419246 |12794086 |15084259 |
SMAD7 | CRCS3 | FLJ16482 | MADH7 | MADH8 | SMAD family member 7 | Phenotypic Suppression | BioGRID | 9892009 |10757800
|
SMURF2 | DKFZp686F0270 | MGC138150 | SMAD specific E3 ubiquitin protein ligase 2 | SMAD3 interacts with SMURF2. | BIND | 15761153 |
- | HPRD,BioGRID | 11016919 |
SNW1 | Bx42 | MGC119379 | NCOA-62 | PRPF45 | Prp45 | SKIIP | SKIP | SNW domain containing 1 | - | HPRD,BioGRID | 11278756 |
SKIP interacts with Smad3. This interaction was modeled on a demonstrated interaction between human SKIP and Smad3 from an unspecified source. | BIND | 11278756 |
SP1 | - | Sp1 transcription factor | Affinity Capture-Western | BioGRID | 11114293 |11432852
|
SPTBN1 | ELF | SPTB2 | betaSpII | spectrin, beta, non-erythrocytic 1 | - | HPRD | 12543979 |
SREBF2 | SREBP2 | bHLHd2 | sterol regulatory element binding transcription factor 2 | SMAD3 interacts with SREBPF2 (SREBP2). | BIND | 15527767 |
STRAP | MAWD | PT-WD | UNRIP | serine/threonine kinase receptor associated protein | - | HPRD,BioGRID | 10757800 |
TFE3 | RCCP2 | TFEA | bHLHe33 | transcription factor binding to IGHM enhancer 3 | - | HPRD | 10557285 |10973944 |12551947 |
Reconstituted Complex | BioGRID | 10557285 |12551947
|
TGFB1I1 | ARA55 | HIC-5 | HIC5 | TSC-5 | transforming growth factor beta 1 induced transcript 1 | ARA55 interacts with Smad3. This interaction was modeled on a demonstrated interaction between human ARA55 and Smad3 from an unspecified species. | BIND | 15561701 |
TGFBR1 | AAT5 | ACVRLK4 | ALK-5 | ALK5 | LDS1A | LDS2A | SKR4 | TGFR-1 | transforming growth factor, beta receptor 1 | - | HPRD | 9311995 |
T-beta-RI phosphorylates hMAD-3. This interaction was modeled on a demonstrated interaction between T-beta-RI from an unspecified species and human hMAD-3. | BIND | 8774881 |
TGFBR2 | AAT3 | FAA3 | LDS1B | LDS2B | MFS2 | RIIC | TAAD2 | TGFR-2 | TGFbeta-RII | transforming growth factor, beta receptor II (70/80kDa) | T-beta-RII phosphorylates hMAD-3. This interaction was modeled on a demonstrated interaction between T-beta-RII from an unspecified species and human hMAD-3. | BIND | 8774881 |
TGIF1 | HPE4 | MGC39747 | MGC5066 | TGIF | TGFB-induced factor homeobox 1 | Affinity Capture-Western | BioGRID | 11427533 |
TGIF2 | - | TGFB-induced factor homeobox 2 | - | HPRD,BioGRID | 11427533 |
TOB1 | APRO6 | MGC104792 | MGC34446 | PIG49 | TOB | TROB | TROB1 | transducer of ERBB2, 1 | - | HPRD | 11163184 |
VDR | NR1I1 | vitamin D (1,25- dihydroxyvitamin D3) receptor | VDR interacts with Smad3. This interaction was modeled on a demonstrated interaction between VDR and Smad3 from unspecified sources. | BIND | 11278756 |
ZEB1 | AREB6 | BZP | DELTA-EF1 | MGC133261 | NIL-2-A | NIL-2A | NIL2A | TCF8 | ZEB | ZFHEP | ZFHX1A | zinc finger E-box binding homeobox 1 | - | HPRD,BioGRID | 12743038 |
ZEB2 | KIAA0569 | SIP-1 | SIP1 | SMADIP1 | ZFHX1B | zinc finger E-box binding homeobox 2 | - | HPRD | 10400677 |
ZFYVE9 | MADHIP | NSP | SARA | SMADIP | zinc finger, FYVE domain containing 9 | - | HPRD,BioGRID | 9865696 |
ZMYM2 | FIM | MYM | RAMP | SCLL | ZNF198 | zinc finger, MYM-type 2 | Smad3 interacts with ZNF198. This interaction was modeled on a demonstrated interaction between human Smad3 and mouse ZNF198. | BIND | 14651998 |
ZNF8 | HF.18 | Zfp128 | zinc finger protein 8 | - | HPRD | 12370310 |