Gene Page: MICB

Summary
GeneID  4277
Symbol  MICB
Synonyms  PERB11.2
Description  MHC class I polypeptide-related sequence B
See related  HGNC:7091|MIM:602436|Ensembl:ENSG00000204516|HPRD:03894|
Locus tag  DAAP-210H10.1
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RAB11FIP30.890.89
SAMD4B0.870.88
TBC1D9B0.850.86
DENND4B0.840.84
FBXL180.840.86
FURIN0.830.85
AC115090.10.830.84
SPATA20.830.84
TTBK10.820.84
POU6F10.820.82
Top 10 negatively co-expressed genes
GNG11-0.59-0.56
C1orf54-0.58-0.57
AL050337.1-0.55-0.56
AF347015.21-0.55-0.47
SYCP3-0.54-0.53
DBI-0.52-0.52
CLEC2B-0.51-0.46
C1orf61-0.50-0.42
RHOC-0.50-0.50
MYL12A-0.49-0.52
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0046703natural killer cell lectin-like receptor bindingIDA11491531 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002429immune response-activating cell surface receptor signaling pathwayIDA11491531 
GO:0019882antigen processing and presentationIEA-
GO:0019835cytolysisIEA-
GO:0009408response to heatIDA9497295 
GO:0006979response to oxidative stressIDA11287116 
GO:0006955immune responseIEA-
GO:0032526response to retinoic acidIDA12569559 
GO:0050689negative regulation of defense response to virus by hostIDA11239445 |12782710 
GO:0044419interspecies interaction between organismsIEA-
GO:0046629gamma-delta T cell activationIDA9497295 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneISS-
GO:0042612MHC class I protein complexIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
KLRC4FLJ17759 | FLJ78582 | NKG2-F | NKG2Fkiller cell lectin-like receptor subfamily C, member 4-HPRD12133964 
KLRK1CD314 | D12S2489E | FLJ17759 | FLJ75772 | KLR | NKG2-D | NKG2Dkiller cell lectin-like receptor subfamily K, member 1-HPRD12902493 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 13792All SZGR genes in this pathway
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN 9251All SZGR genes in this pathway
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP 206111All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
BENPORATH_ES_1 379235All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_2 11476All SZGR genes in this pathway
PENG_GLUCOSE_DEPRIVATION_DN 169112All SZGR genes in this pathway
CROMER_METASTASIS_UP 7946All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP 3022All SZGR genes in this pathway
FAELT_B_CLL_WITH_VH3_21_DN 4929All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_UP 198132All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_DN 318220All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G6 153112All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP 7747All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN 4126All SZGR genes in this pathway
FUJII_YBX1_TARGETS_DN 202132All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_UP 181106All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED 351238All SZGR genes in this pathway
UROSEVIC_RESPONSE_TO_IMIQUIMOD 2314All SZGR genes in this pathway
STEIN_ESR1_TARGETS 8555All SZGR genes in this pathway
SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP 8363All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP 324193All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
LINSLEY_MIR16_TARGETS 206127All SZGR genes in this pathway
WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 5739All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 403240All SZGR genes in this pathway


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