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GeneID |
4287
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Symbol |
ATXN3
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Synonyms |
AT3|ATX3|JOS|MJD|MJD1|SCA3
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Description |
ataxin 3 |
See related |
HGNC:7106|MIM:607047|Ensembl:ENSG00000066427|HPRD:06131| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
14q24.3-q32.2 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Association | A combined odds ratio method (Sun et al. 2008), association studies | 1 | Link to SZGene | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 2 | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.0248 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
FSTL1 | 0.78 | 0.77 | | |
NID1 | 0.78 | 0.81 | | |
NAGA | 0.78 | 0.73 | | |
MMP14 | 0.77 | 0.73 | | |
LAMA4 | 0.77 | 0.77 | | |
HAPLN3 | 0.77 | 0.74 | | |
HTRA3 | 0.75 | 0.76 | | |
FLVCR2 | 0.75 | 0.64 | | |
CXCL12 | 0.75 | 0.64 | | |
STRA6 | 0.75 | 0.72 | | |
Top 10 negatively co-expressed genes | SEPT4 | -0.42 | -0.51 | | |
S100A1 | -0.42 | -0.47 | | |
C5orf53 | -0.40 | -0.50 | | |
AF347015.27 | -0.40 | -0.51 | | |
AF347015.33 | -0.40 | -0.51 | | |
HHATL | -0.39 | -0.50 | | |
MT-CO2 | -0.39 | -0.51 | | |
ASPA | -0.38 | -0.45 | | |
AP000907.5 | -0.38 | -0.44 | | |
CRYAB | -0.38 | -0.44 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005515 | protein binding | IPI | | 16713569 |
GO:0016787 | hydrolase activity | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007268 | synaptic transmission | TAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 7655453 |
GO:0007399 | nervous system development | TAS | neurite (GO term level: 5) | 9124802 |
GO:0006355 | regulation of transcription, DNA-dependent | IEA | | - |
GO:0006350 | transcription | IEA | | - |
GO:0006289 | nucleotide-excision repair | TAS | | 10915768 |
GO:0008219 | cell death | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005634 | nucleus | IEA | | - |
GO:0005654 | nucleoplasm | TAS | | 9580663 |
GO:0005737 | cytoplasm | TAS | | 9124802 |
GO:0016363 | nuclear matrix | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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