Gene Page: MSH4

Summary
GeneID  4438
Symbol  MSH4
Synonyms  -
Description  mutS homolog 4 (E. coli)
See related  HGNC:7327|MIM:602105|Ensembl:ENSG00000057468|HPRD:03658|
Locus tag  RP11-262K24.2
Gene type  protein-coding
Map location  1p31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02692 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003677DNA bindingTAS9299235 
GO:0005524ATP bindingIEA-
GO:0030983mismatched DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007129synapsisIEASynap (GO term level: 10)-
GO:0001541ovarian follicle developmentIEA-
GO:0007131reciprocal meiotic recombinationTAS9299235 
GO:0006298mismatch repairIEA-
GO:0007292female gamete generationIEA-
GO:0007283spermatogenesisIEA-
GO:0007126meiosisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000793condensed chromosomeIEA-
GO:0000795synaptonemal complexIEA-
GO:0005634nucleusTAS9299235 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MLH1COCA2 | FCC2 | HNPCC | HNPCC2 | MGC5172 | hMLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)MLH1 interacts with MSH4.BIND10928988 
-HPRD,BioGRID10928988 
MLH3HNPCC7 | MGC138372mutL homolog 3 (E. coli)-HPRD,BioGRID12095912 
MSH5DKFZp434C1615 | G7 | MGC2939 | MutSH5 | NG23mutS homolog 5 (E. coli)-HPRD,BioGRID9787078 |10029069 
hMSH4 interacts with hMSH5.BIND15304223 
RAD51BRCC5 | HRAD51 | HsRad51 | HsT16930 | RAD51A | RECARAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)Co-localizationBioGRID11950880 
RPA1HSSB | REPA1 | RF-A | RP-A | RPA70replication protein A1, 70kDaCo-localizationBioGRID11950880 
VBP1PFD3 | PFDN3 | VBP-1von Hippel-Lindau binding protein 1-HPRD,BioGRID12591739 
 


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