Gene Page: MTRR

Summary
GeneID  4552
Symbol  MTRR
Synonyms  MGC129643|MSR
Description  5-methyltetrahydrofolate-homocysteine methyltransferase reductase
See related  HGNC:7473|MIM:602568|Ensembl:ENSG00000124275|HPRD:03979|
Locus tag  -
Gene type  protein-coding
Map location  5p15.3-p15.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005506iron ion bindingIEA-
GO:0016740transferase activityIEA-
GO:0008168methyltransferase activityIEA-
GO:0010181FMN bindingIEA-
GO:0010181FMN bindingTAS9501215 
GO:0009055electron carrier activityIEA-
GO:0016491oxidoreductase activityIEA-
GO:0030586[methionine synthase] reductase activityTAS9501215 
GO:0050660FAD bindingTAS9501215 
GO:0050661NADP bindingTAS9501215 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009086methionine biosynthetic processIEA-
GO:0008652amino acid biosynthetic processIEA-
GO:0055114oxidation reductionTAS9501215 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolTAS9501215 
GO:0005737cytoplasmIEA-
GO:0005739mitochondrionIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
TIEN_INTESTINE_PROBIOTICS_6HR_DN 167100All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
MIDORIKAWA_AMPLIFIED_IN_LIVER_CANCER 5538All SZGR genes in this pathway
LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER 214139All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_DN 6045All SZGR genes in this pathway
LEIN_OLIGODENDROCYTE_MARKERS 7453All SZGR genes in this pathway
WONG_MITOCHONDRIA_GENE_MODULE 217122All SZGR genes in this pathway
LU_EZH2_TARGETS_DN 414237All SZGR genes in this pathway
ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP 8451All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
ZWANG_EGF_PERSISTENTLY_DN 6136All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-3615385451A,m8hsa-miR-361brainUUAUCAGAAUCUCCAGGGGUAC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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