Gene Page: MYF6

Summary
GeneID  4618
Symbol  MYF6
Synonyms  MRF4|bHLHc4
Description  myogenic factor 6 (herculin)
See related  HGNC:7566|MIM:159991|Ensembl:ENSG00000111046|HPRD:01169|
Locus tag  -
Gene type  protein-coding
Map location  12q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CDKL50.940.96
FAM126B0.940.96
PLEKHM30.940.95
LONRF20.930.96
HECW20.930.94
C9orf1260.930.92
MYCBP20.920.92
TMOD20.920.93
LMTK20.920.93
MAP20.920.94
Top 10 negatively co-expressed genes
RAB34-0.57-0.65
DBI-0.55-0.65
RHOC-0.55-0.65
ACSF2-0.55-0.61
EFEMP2-0.54-0.57
EIF4EBP3-0.54-0.60
C1orf61-0.54-0.74
TLCD1-0.54-0.57
FXYD1-0.53-0.57
ENHO-0.53-0.62
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS2311584 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007519skeletal muscle developmentTASneuron (GO term level: 8)2311584 
GO:0001756somitogenesisIEA-
GO:0006357regulation of transcription from RNA polymerase II promoterTAS2311584 
GO:0007517muscle developmentIEA-
GO:0007275multicellular organismal developmentIEA-
GO:0016481negative regulation of transcriptionIEA-
GO:0030154cell differentiationIEA-
GO:0045941positive regulation of transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusTAS2311584 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALM1CALML2 | CAMI | DD132 | PHKDcalmodulin 1 (phosphorylase kinase, delta)-HPRD10757985 
CALM2CAMII | PHKD | PHKD2calmodulin 2 (phosphorylase kinase, delta)-HPRD10757985 
CALM3PHKD | PHKD3calmodulin 3 (phosphorylase kinase, delta)-HPRD10757985 
CSRP3CLP | CMD1M | CMH12 | CRP3 | LMO4 | MGC14488 | MGC61993 | MLPcysteine and glycine-rich protein 3 (cardiac LIM protein)-HPRD,BioGRID9234731 
ELSPBP1E12 | HE12epididymal sperm binding protein 1Two-hybridBioGRID9242638 
ID1ID | bHLHb24inhibitor of DNA binding 1, dominant negative helix-loop-helix proteinAffinity Capture-WesternBioGRID9242638 
ID2GIG8 | ID2A | ID2H | MGC26389 | bHLHb26inhibitor of DNA binding 2, dominant negative helix-loop-helix proteinAffinity Capture-WesternBioGRID9242638 
ID3HEIR-1 | bHLHb25inhibitor of DNA binding 3, dominant negative helix-loop-helix proteinAffinity Capture-WesternBioGRID9242638 
TCF3E2A | ITF1 | MGC129647 | MGC129648 | bHLHb21transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)Two-hybridBioGRID9242638 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_CMYB_PATHWAY 8461All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_MYOGENESIS 2820All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_FLI1 98All SZGR genes in this pathway
HASLINGER_B_CLL_WITH_CHROMOSOME_12_TRISOMY 2412All SZGR genes in this pathway
SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1B 2314All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_DN 228146All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G1 6741All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN 228114All SZGR genes in this pathway
BASSO_HAIRY_CELL_LEUKEMIA_DN 8066All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN 264159All SZGR genes in this pathway
SUZUKI_CTCFL_TARGETS_UP 125All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-299-5p422428m8hsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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