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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: MYOD1

Summary

GeneID

4654

Symbol

MYOD1

Synonyms

MYF3|MYOD|PUM|bHLHc1

Description

myogenic differentiation 1

Locus tag

Gene type

protein-coding

Map location

11p15.4

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Expression

P value: 1.818

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003705

RNA polymerase II transcription factor activity, enhancer binding

TAS

1846704

GO:0003713

transcription coactivator activity

TAS

1846704

GO:0008134

transcription factor binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007519

skeletal muscle development

TAS

neuron (GO term level: 8)

3175662

GO:0006357

regulation of transcription from RNA polymerase II promoter

TAS

1846704

GO:0006468

protein amino acid phosphorylation

TAS

3175662

GO:0007518

myoblast cell fate determination

IEA

GO:0007517

muscle development

TAS

1846704

GO:0007275

multicellular organismal development

IEA

GO:0030154

cell differentiation

IEA

GO:0045445

myoblast differentiation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

TAS

3175662

GO:0005667

transcription factor complex

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ASCL3	HASH3 \| SGN1 \| bHLHa42	achaete-scute complex homolog 3 (Drosophila)	-	HPRD	11784080
BHLHB3	DEC2 \| SHARP-1 \| SHARP1 \| bHLHe41	basic helix-loop-helix domain containing, class B, 3	-	HPRD	12657651
BHLHB8	MIST1 \| bHLHa15	basic helix-loop-helix domain containing, class B, 8	-	HPRD	9482738
BTG1	-	B-cell translocation gene 1, anti-proliferative	BTG1 interacts with MYOD1 (CMD1). This interaction was modeled on a demonstrated interaction between human BTG1 and chicken CMD1.	BIND	15674337
CALM1	CALML2 \| CAMI \| DD132 \| PHKD	calmodulin 1 (phosphorylase kinase, delta)	-	HPRD	10757985
CALM2	CAMII \| PHKD \| PHKD2	calmodulin 2 (phosphorylase kinase, delta)	-	HPRD	10757985
CALM3	PHKD \| PHKD3	calmodulin 3 (phosphorylase kinase, delta)	-	HPRD	10757985
CDC34	E2-CDC34 \| UBC3 \| UBE2R1	cell division cycle 34 homolog (S. cerevisiae)	-	HPRD	9710583
CDK4	CMM3 \| MGC14458 \| PSK-J3	cyclin-dependent kinase 4	-	HPRD,BioGRID	10022835 \|10601020
CDKN1C	BWCR \| BWS \| KIP2 \| WBS \| p57	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	-	HPRD,BioGRID	10764802
CIB2	KIP2	calcium and integrin binding family member 2	-	HPRD	10764802
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	Affinity Capture-Western Phenotypic Enhancement Reconstituted Complex	BioGRID	9001254 \|11463815
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	-	HPRD	2176177 \|9238849 \|11463815
CSRP3	CLP \| CMD1M \| CMH12 \| CRP3 \| LMO4 \| MGC14488 \| MGC61993 \| MLP	cysteine and glycine-rich protein 3 (cardiac LIM protein)	-	HPRD,BioGRID	9234731
ELSPBP1	E12 \| HE12	epididymal sperm binding protein 1	Two-hybrid	BioGRID	9242638
EP300	KAT3B \| p300	E1A binding protein p300	-	HPRD,BioGRID	9001254
EP300	KAT3B \| p300	E1A binding protein p300	p300 interacts with MyoD. This interaction is modelled on a demonstrated interaction between human and mouse p300 and MyoD from mouse and an unspecified species.	BIND	8621548
HAND1	Hxt \| Thing1 \| bHLHa27 \| eHand	heart and neural crest derivatives expressed 1	-	HPRD	10924525
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	-	HPRD,BioGRID	11285237 \|11684023
HEY1	BHLHb31 \| CHF2 \| HERP2 \| HESR1 \| HRT-1 \| MGC1274 \| OAF1	hairy/enhancer-of-split related with YRPW motif 1	-	HPRD,BioGRID	11279181
HSP90AA1	FLJ31884 \| HSP86 \| HSP89A \| HSP90A \| HSP90N \| HSPC1 \| HSPCA \| HSPCAL1 \| HSPCAL4 \| HSPN \| Hsp89 \| Hsp90 \| LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	-	HPRD,BioGRID	1406681
ID1	ID \| bHLHb24	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	Affinity Capture-Western Two-hybrid	BioGRID	8380166 \|9242638 \|9528857 \|15029197
ID2	GIG8 \| ID2A \| ID2H \| MGC26389 \| bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	-	HPRD,BioGRID	9242638
ID3	HEIR-1 \| bHLHb25	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	-	HPRD,BioGRID	8759016 \|9242638
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	-	HPRD,BioGRID	1310896
MDFI	I-MF \| I-mfa	MyoD family inhibitor	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	8797820
MEF2A	ADCAD1 \| RSRFC4 \| RSRFC9	myocyte enhancer factor 2A	-	HPRD	8548800\|9418854
MEF2C	-	myocyte enhancer factor 2C	Two-hybrid	BioGRID	9418854
MOS	MGC119962 \| MGC119963 \| MSV	v-mos Moloney murine sarcoma viral oncogene homolog	-	HPRD,BioGRID	9001211
MYOD1	MYF3 \| MYOD \| PUM \| bHLHc1	myogenic differentiation 1	Reconstituted Complex	BioGRID	9184158
NCOR1	KIAA1047 \| MGC104216 \| N-CoR \| TRAC1 \| hCIT529I10 \| hN-CoR	nuclear receptor co-repressor 1	Reconstituted Complex	BioGRID	10406466
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	nuclear receptor co-repressor 2	-	HPRD	10406466
NR2F2	ARP1 \| COUP-TFII \| COUPTFB \| MGC117452 \| SVP40 \| TFCOUP2	nuclear receptor subfamily 2, group F, member 2	-	HPRD,BioGRID	9826778
PABPN1	OPMD \| PAB2 \| PABP2	poly(A) binding protein, nuclear 1	Affinity Capture-Western	BioGRID	11371506
PSMD4	AF \| AF-1 \| ASF \| MCB1 \| Rpn10 \| S5A \| pUB-R5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	-	HPRD,BioGRID	9235903
RB1	OSRC \| RB \| p105-Rb \| pRb \| pp110	retinoblastoma 1	-	HPRD,BioGRID	8381715
RORA	DKFZp686M2414 \| MGC119326 \| MGC119329 \| NR1F1 \| ROR1 \| ROR2 \| ROR3 \| RZR-ALPHA \| RZRA	RAR-related orphan receptor A	-	HPRD,BioGRID	9862959
RXRA	FLJ00280 \| FLJ00318 \| FLJ16020 \| FLJ16733 \| MGC102720 \| NR2B1	retinoid X receptor, alpha	-	HPRD,BioGRID	9692544
SNW1	Bx42 \| MGC119379 \| NCOA-62 \| PRPF45 \| Prp45 \| SKIIP \| SKIP	SNW domain containing 1	Affinity Capture-Western	BioGRID	11371506
SP1	-	Sp1 transcription factor	-	HPRD,BioGRID	10082523
SRF	MCM1	serum response factor (c-fos serum response element-binding transcription factor)	-	HPRD	8617811
STAT3	APRF \| FLJ20882 \| HIES \| MGC16063	signal transducer and activator of transcription 3 (acute-phase response factor)	-	HPRD,BioGRID	12947115
TCF3	E2A \| ITF1 \| MGC129647 \| MGC129648 \| bHLHb21	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	-	HPRD	1649701 \|9001211 \|9184158
TCF3	E2A \| ITF1 \| MGC129647 \| MGC129648 \| bHLHb21		in vitro in vivo Reconstituted Complex Two-hybrid	BioGRID	1649701 \|9184158 \|9242638
TCF4	E2-2 \| ITF2 \| MGC149723 \| MGC149724 \| PTHS \| SEF2 \| SEF2-1 \| SEF2-1A \| SEF2-1B \| bHLHb19	transcription factor 4	-	HPRD,BioGRID	8576241 \|8999959
TWIST1	ACS3 \| BPES2 \| BPES3 \| SCS \| TWIST \| bHLHa38	twist homolog 1 (Drosophila)	-	HPRD	9343420

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
BIOCARTA_HDAC_PATHWAY	32	25	All SZGR genes in this pathway
PID_SMAD2_3NUCLEAR_PATHWAY	82	63	All SZGR genes in this pathway
PID_HDAC_CLASSIII_PATHWAY	25	20	All SZGR genes in this pathway
PID_CMYB_PATHWAY	84	61	All SZGR genes in this pathway
PID_RB_1PATHWAY	65	46	All SZGR genes in this pathway
PID_HES_HEY_PATHWAY	48	39	All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY	396	292	All SZGR genes in this pathway
REACTOME_MYOGENESIS	28	20	All SZGR genes in this pathway
DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP	59	38	All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP	332	228	All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP	255	177	All SZGR genes in this pathway
DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP	64	37	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
MARKS_ACETYLATED_NON_HISTONE_PROTEINS	15	9	All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK	1652	1023	All SZGR genes in this pathway
SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER	88	64	All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS	1038	678	All SZGR genes in this pathway
BENPORATH_EED_TARGETS	1062	725	All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3	1118	744	All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS	652	441	All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_UP	98	64	All SZGR genes in this pathway
DELASERNA_MYOD_TARGETS_UP	89	51	All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL	311	205	All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP	268	157	All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN	161	105	All SZGR genes in this pathway
LOPES_METHYLATED_IN_COLON_CANCER_UP	27	20	All SZGR genes in this pathway
NIKOLSKY_OVERCONNECTED_IN_BREAST_CANCER	22	19	All SZGR genes in this pathway
YAMASHITA_METHYLATED_IN_PROSTATE_CANCER	57	29	All SZGR genes in this pathway
GRADE_COLON_CANCER_UP	871	505	All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	536	296	All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K27ME3	269	159	All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	435	318	All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3	590	403	All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP	857	456	All SZGR genes in this pathway