Gene Page: NCAM2

Summary
GeneID  4685
Symbol  NCAM2
Synonyms  MGC51008|NCAM21
Description  neural cell adhesion molecule 2
See related  HGNC:7657|MIM:602040|Ensembl:ENSG00000154654|HPRD:03619|
Locus tag  -
Gene type  protein-coding
Map location  21q21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AC025647.10.910.89
MRPS330.880.80
TMEM126B0.870.87
C2orf640.870.78
C1orf570.860.79
PTS0.860.86
PPA20.860.79
NDUFA90.860.79
NDUFA40.850.78
SDHB0.850.81
Top 10 negatively co-expressed genes
SMTN-0.52-0.69
SLC19A1-0.51-0.55
SEMA4B-0.50-0.60
DMPK-0.50-0.60
HIP1R-0.50-0.55
TNKS1BP1-0.49-0.48
GLIS2-0.48-0.59
CRIPAK-0.48-0.59
HDAC7-0.48-0.63
MYO9B-0.47-0.53
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007158neuron adhesionTASneuron (GO term level: 5)9226371 
GO:0007155cell adhesionIEA-
GO:0007166cell surface receptor linked signal transductionIEA-
GO:0034109homotypic cell-cell adhesionIEA-
GO:0050850positive regulation of calcium-mediated signalingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0030424axonIEAneuron, axon, Neurotransmitter (GO term level: 6)-
GO:0016021integral to membraneTAS9226371 
GO:0009897external side of plasma membraneIEA-
GO:0005886plasma membraneTAS9226371 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ESR1DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1estrogen receptor 1ER interacts with NCAM2.BIND16009131 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
KEGG_PRION_DISEASES 3528All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN 275168All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP 276165All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP 13983All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_UP 3024All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
YEGNASUBRAMANIAN_PROSTATE_CANCER 12860All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN 264159All SZGR genes in this pathway
FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_UP 2414All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP 397206All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 11066All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-125/3514945001Ahsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
miR-4952032091Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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