Gene Page: NEB

Summary
GeneID  4703
Symbol  NEB
Synonyms  DKFZp686C1456|FLJ11505|FLJ36536|FLJ39568|FLJ39584|NEB177D|NEM2
Description  nebulin
See related  HGNC:7720|MIM:161650|Ensembl:ENSG00000183091|HPRD:01196|
Locus tag  -
Gene type  protein-coding
Map location  2q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02395 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TMEM126A0.890.85
MRPS150.880.87
MGST30.870.80
DNAJC190.870.85
UBL50.860.78
NDUFS30.860.81
COX7B0.860.83
NDUFB60.860.79
CMC10.860.83
C14orf20.850.83
Top 10 negatively co-expressed genes
LRP1-0.52-0.50
MTSS1L-0.48-0.49
MAP4K4-0.48-0.50
PXN-0.48-0.58
PHLDB1-0.47-0.48
SMTN-0.47-0.58
SLC19A1-0.47-0.48
STK10-0.47-0.52
TNKS1BP1-0.46-0.43
AC005035.1-0.46-0.47
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIEA-
GO:0005515protein bindingIPI15967462 
GO:0008307structural constituent of muscleTAS7739042 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007525somatic muscle developmentNAS7739042 
GO:0030832regulation of actin filament lengthNAS7739042 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0030018Z discIDA9501083 
GO:0015629actin cytoskeletonTAS7739042 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTN4ACTININ-4 | DKFZp686K23158 | FSGS | FSGS1actinin, alpha 4-HPRD11882289 
DESCMD1I | CSM1 | CSM2 | FLJ12025 | FLJ39719 | FLJ41013 | FLJ41793desminTwo-hybridBioGRID11309420 
MYPNMYOPmyopalladin-HPRD,BioGRID11309420 |12482578 
TMOD1D9S57E | ETMOD | TMODtropomodulin 1-HPRD,BioGRID11016930 
TMOD4DKFZp779I0852 | SK-TMODtropomodulin 4 (muscle)Reconstituted ComplexBioGRID11016930 
TRIM55MURF-2 | RNF29tripartite motif-containing 55MURF-2 interacts with Nebulin.BIND15967462 
TTNCMD1G | CMH9 | CMPD4 | CONNECTIN | DKFZp451N061 | EOMFC | FLJ26020 | FLJ26409 | FLJ32040 | FLJ34413 | FLJ39564 | FLJ43066 | HMERF | LGMD2J | TMDtitin-HPRD11851340 |12482578 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_STRIATED_MUSCLE_CONTRACTION 2712All SZGR genes in this pathway
REACTOME_MUSCLE_CONTRACTION 4824All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN 6849All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN 537339All SZGR genes in this pathway
DELYS_THYROID_CANCER_DN 232154All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_F 5432All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_UP 6446All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
GHO_ATF5_TARGETS_UP 1310All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P4 10062All SZGR genes in this pathway
SANSOM_APC_TARGETS 212121All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_UP 14175All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN 264159All SZGR genes in this pathway
PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_DN 2911All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_EARLY_LATE 317190All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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