Gene Page: NFATC4

Summary
GeneID  4776
Symbol  NFATC4
Synonyms  NF-ATc4|NFAT3
Description  nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
See related  HGNC:7778|MIM:602699|Ensembl:ENSG00000100968|HPRD:09096|
Locus tag  -
Gene type  protein-coding
Map location  14q11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
EOMES0.910.55
DMRTA20.890.56
COL4A60.880.56
SOX30.870.41
TFAP2C0.860.55
BOC0.830.64
CELSR10.830.62
GLI30.820.46
PHLDA10.810.68
LRIG30.800.47
Top 10 negatively co-expressed genes
C5orf53-0.32-0.52
LGI4-0.31-0.20
AIFM3-0.31-0.49
PTH1R-0.31-0.48
ABCG2-0.31-0.39
HLA-F-0.30-0.44
FBXO2-0.30-0.28
SLC16A11-0.30-0.37
LHPP-0.30-0.31
AF347015.27-0.29-0.62
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0003713transcription coactivator activityTAS7749981 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006366transcription from RNA polymerase II promoterTAS7749981 
GO:0007507heart developmentIEA-
GO:0006954inflammatory responseTAS7749981 
GO:0045333cellular respirationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CREBBPCBP | KAT3A | RSTSCREB binding protein-HPRD,BioGRID11514544 
GATA4MGC126629GATA binding protein 4-HPRD,BioGRID9568714 
YWHAQ14-3-3 | 1C5 | HS1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide-HPRD,BioGRID10611249 
YWHAZKCIP-1 | MGC111427 | MGC126532 | MGC138156tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide-HPRD,BioGRID10611249 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-29180186m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-32893991Ahsa-miR-328brainCUGGCCCUCUCUGCCCUUCCGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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