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GeneID |
4821
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Symbol |
NKX2-2
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Synonyms |
NKX2.2|NKX2B
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Description |
NK2 homeobox 2 |
See related |
HGNC:7835|MIM:604612|Ensembl:ENSG00000125820|HPRD:05213| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
20pter-q11.23 |
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Gene set name |
Method of gene set |
Evidence |
Info |
GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 5 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
CORT | 0.69 | 0.71 | | |
APITD1 | 0.68 | 0.69 | | |
EXOC3L | 0.65 | 0.48 | | |
LRRC56 | 0.64 | 0.69 | | |
PLCB2 | 0.63 | 0.66 | | |
KRTCAP3 | 0.61 | 0.33 | | |
WFDC2 | 0.59 | 0.58 | | |
RPP25 | 0.59 | 0.59 | | |
RXRG | 0.59 | 0.31 | | |
CASZ1 | 0.58 | 0.44 | | |
Top 10 negatively co-expressed genes | NET1 | -0.31 | -0.33 | | |
AF347015.2 | -0.30 | -0.25 | | |
AF347015.26 | -0.29 | -0.29 | | |
AF347015.15 | -0.28 | -0.25 | | |
MT-CYB | -0.28 | -0.25 | | |
PREX2 | -0.27 | -0.30 | | |
AF347015.8 | -0.27 | -0.23 | | |
PITPNC1 | -0.27 | -0.26 | | |
PTRF | -0.27 | -0.23 | | |
EGLN3 | -0.26 | -0.23 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0003700 | transcription factor activity | IEA | | - |
GO:0005515 | protein binding | IEA | | - |
GO:0043565 | sequence-specific DNA binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007420 | brain development | TAS | Brain (GO term level: 7) | 1346742 |
GO:0048665 | neuron fate specification | IEA | neuron (GO term level: 10) | - |
GO:0014003 | oligodendrocyte development | IEA | axon, oligodendrocyte, Glial (GO term level: 10) | - |
GO:0021529 | spinal cord oligodendrocyte cell differentiation | IEA | neuron, axon, oligodendrocyte (GO term level: 10) | - |
GO:0007399 | nervous system development | IEA | neurite (GO term level: 5) | - |
GO:0006355 | regulation of transcription, DNA-dependent | IEA | | - |
GO:0048468 | cell development | IEA | | - |
GO:0007275 | multicellular organismal development | IEA | | - |
GO:0031018 | endocrine pancreas development | IEA | | - |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | IEA | | - |
GO:0045597 | positive regulation of cell differentiation | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005634 | nucleus | IEA | | - |
GO:0005730 | nucleolus | IDA | | 18029348 |
GO:0005737 | cytoplasm | IDA | | 18029348 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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