Gene Page: NMT1

Summary
GeneID  4836
Symbol  NMT1
Synonyms  NMT
Description  N-myristoyltransferase 1
See related  HGNC:7857|MIM:160993|Ensembl:ENSG00000136448|HPRD:01187|
Locus tag  -
Gene type  protein-coding
Map location  17q21.31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0351 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TSNAXIP10.850.64
WDR660.850.69
DLEC10.830.56
CCDC390.830.64
AC079354.20.830.62
C7orf630.830.65
DNAH20.820.59
LRP2BP0.820.53
RPGR0.820.55
ZBBX0.820.61
Top 10 negatively co-expressed genes
TBR1-0.34-0.25
SOX5-0.33-0.16
AFF3-0.32-0.15
ID2-0.32-0.29
NEUROD2-0.31-0.21
PRDM8-0.31-0.21
BACH2-0.31-0.12
DAB1-0.31-0.14
TSHZ3-0.31-0.17
KCTD12-0.31-0.19
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004379glycylpeptide N-tetradecanoyltransferase activityIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001701in utero embryonic developmentIEA-
GO:0006499N-terminal protein myristoylationNAS-
GO:0009249protein lipoylationTAS9506952 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP11099414 
GO:0005575cellular_componentND-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YESBiochemical ActivityBioGRID11594778 
LYNFLJ26625 | JTK8v-yes-1 Yamaguchi sarcoma viral related oncogene homolog-HPRD,BioGRID11594778 
MARCKS80K-L | FLJ14368 | FLJ90045 | MACS | MRACKS | PKCSL | PRKCSLmyristoylated alanine-rich protein kinase C substratehNMT1 interacts with and myristoylates MARCKS.BIND10734119 
PRKACAMGC102831 | MGC48865 | PKACAprotein kinase, cAMP-dependent, catalytic, alphahNMT1 interacts with and myristoylates PRKACA.BIND10734119 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_APOPTOSIS 14894All SZGR genes in this pathway
REACTOME_HIV_INFECTION 207122All SZGR genes in this pathway
REACTOME_HIV_LIFE_CYCLE 12569All SZGR genes in this pathway
REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 10461All SZGR genes in this pathway
REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS 3021All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
HAHTOLA_SEZARY_SYNDROM_UP 9858All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN 14295All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN 153100All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
RICKMAN_METASTASIS_UP 344180All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
PENG_LEUCINE_DEPRIVATION_DN 187122All SZGR genes in this pathway
BECKER_TAMOXIFEN_RESISTANCE_UP 5036All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_DN 245154All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN 7345All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN 172107All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C4 2014All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_DN 228146All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
TSENG_IRS1_TARGETS_UP 11371All SZGR genes in this pathway
KRASNOSELSKAYA_ILF3_TARGETS_DN 4638All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_DN 14192All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_4NQO_OR_UV 6344All SZGR genes in this pathway
KYNG_DNA_DAMAGE_DN 195135All SZGR genes in this pathway
ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN 354216All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP 298174All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP 129All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN 253192All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 172107All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK 14582All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/50610601066m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-138289829041Ahsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-143333833441Ahsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-204/2112512571Ahsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
miR-2142632691Ahsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-3305705761Ahsa-miR-330brainGCAAAGCACACGGCCUGCAGAGA
miR-362379385m8hsa-miR-362AAUCCUUGGAACCUAGGUGUGAGU
miR-369-3p3313371Ahsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-374331337m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-4103333391Ahsa-miR-410AAUAUAACACAGAUGGCCUGU
miR-493-5p3743811A,m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-77427481Ahsa-miR-7SZUGGAAGACUAGUGAUUUUGUUG
miR-9182118281A,m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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