Gene Page: OPRD1

Summary
GeneID  4985
Symbol  OPRD1
Synonyms  OPRD
Description  opioid receptor, delta 1
See related  HGNC:8153|MIM:165195|Ensembl:ENSG00000116329|HPRD:01308|
Locus tag  -
Gene type  protein-coding
Map location  1p36.1-p34.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0723 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004986delta-opioid receptor activityTAS9548483 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007218neuropeptide signaling pathwayIEANeurotransmitter (GO term level: 8)-
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messengerTAS7808419 
GO:0007193G-protein signaling, adenylate cyclase inhibiting pathwayIEA-
GO:0007165signal transductionIEA-
GO:0008344adult locomotory behaviorIEA-
GO:0006955immune responseTAS9548483 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionIEA-
GO:0005886plasma membraneTAS10788493 
GO:0005887integral to plasma membraneTAS7808419 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADRB2ADRB2R | ADRBR | B2AR | BAR | BETA2ARadrenergic, beta-2-, receptor, surface-HPRD,BioGRID11278447 
ARRB1ARB1 | ARR1arrestin, beta 1-HPRD,BioGRID11259507 
ARRB2ARB2 | ARR2 | BARR2 | DKFZp686L0365arrestin, beta 2-HPRD,BioGRID11259507 
GNA15GNA16guanine nucleotide binding protein (G protein), alpha 15 (Gq class)-HPRD14535952 
GNAI2GIP | GNAI2B | H_LUCA15.1 | H_LUCA16.1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2-HPRD,BioGRID1671672 
GNAO1DKFZp686O0962 | G-ALPHA-o | GNAOguanine nucleotide binding protein (G protein), alpha activating activity polypeptide O-HPRD,BioGRID8393523 
GNAZ-guanine nucleotide binding protein (G protein), alpha z polypeptide-HPRD9166747 
GPRASP1GASP | GASP1 | KIAA0443G protein-coupled receptor associated sorting protein 1-HPRD,BioGRID12142540 
GASP-1 interacts with DOR.BIND15086532 
OPRD1OPRDopioid receptor, delta 1Affinity Capture-Western
FRET
BioGRID11278447 
OPRK1KOR | OPRKopioid receptor, kappa 1-HPRD11069979 
OPRM1KIAA0403 | MOR | MOR1 | OPRMopioid receptor, mu 1-HPRD,BioGRID11069979 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
DAWSON_METHYLATED_IN_LYMPHOMA_TCL1 5945All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM5 9459All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_NEOCORTEX_UP 8366All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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