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GeneID |
4988
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Symbol |
OPRM1
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Synonyms |
KIAA0403|MOR|MOR1|OPRM
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Description |
opioid receptor, mu 1 |
See related |
HGNC:8156|MIM:600018|Ensembl:ENSG00000112038|HPRD:02484| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
6q24-q25 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.006 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
AVP | 1.00 | 0.27 | | |
HCRT | 1.00 | 0.08 | | |
PMCH | 0.99 | -0.01 | | |
TMEM190 | 0.98 | 0.05 | | |
FMO3 | 0.95 | 0.05 | | |
TMEM146 | 0.94 | -0.02 | | |
FAM81B | 0.94 | -0.00 | | |
WDR38 | 0.93 | 0.05 | | |
CD36 | 0.93 | -0.15 | | |
STOML3 | 0.92 | -0.08 | | |
Top 10 negatively co-expressed genes | AC008073.2 | -0.09 | 0.02 | | |
FBXO32 | -0.08 | 0.04 | | |
NDRG1 | -0.08 | -0.06 | | |
RTN4RL2 | -0.07 | 0.05 | | |
CD163L1 | -0.07 | 0.12 | | |
MGLL | -0.07 | 0.07 | | |
AC016910.1 | -0.07 | -0.06 | | |
ARHGEF2 | -0.07 | -0.03 | | |
DUSP1 | -0.07 | 0.02 | | |
SLC26A4 | -0.07 | 0.02 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0004872 | receptor activity | IEA | | - |
GO:0004988 | mu-opioid receptor activity | IEA | | - |
GO:0004988 | mu-opioid receptor activity | TAS | | 9689128 |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007191 | dopamine receptor, adenylate cyclase activating pathway | IEA | dopamine (GO term level: 12) | - |
GO:0007187 | G-protein signaling, coupled to cyclic nucleotide second messenger | TAS | | 7905839 |
GO:0007186 | G-protein coupled receptor protein signaling pathway | IEA | | - |
GO:0007193 | G-protein signaling, adenylate cyclase inhibiting pathway | IEA | | - |
GO:0007165 | signal transduction | IEA | | - |
GO:0008285 | negative regulation of cell proliferation | TAS | | 2159143 |
GO:0007626 | locomotory behavior | IEA | | - |
GO:0007600 | sensory perception | TAS | | 9689128 |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005794 | Golgi apparatus | TAS | | 9242668 |
GO:0005624 | membrane fraction | IEA | | - |
GO:0005783 | endoplasmic reticulum | TAS | | 9242668 |
GO:0016021 | integral to membrane | IEA | | - |
GO:0005886 | plasma membrane | TAS | | 9242668 |
GO:0005887 | integral to plasma membrane | TAS | | 7905839 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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