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GeneID |
5015
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Symbol |
OTX2
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Synonyms |
MCOPS5|MGC45000
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Description |
orthodenticle homeobox 2 |
See related |
HGNC:8522|MIM:600037|Ensembl:ENSG00000165588|HPRD:07190| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
14q21-q22 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 6 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
Top 10 negatively co-expressed genes | |
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0003700 | transcription factor activity | NAS | | - |
GO:0005515 | protein binding | IEA | | - |
GO:0008190 | eukaryotic initiation factor 4E binding | TAS | | 15705863 |
GO:0043565 | sequence-specific DNA binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007417 | central nervous system development | IEA | Brain (GO term level: 6) | - |
GO:0007411 | axon guidance | IDA | axon (GO term level: 13) | 16267555 |
GO:0048663 | neuron fate commitment | IEA | neuron (GO term level: 9) | - |
GO:0030901 | midbrain development | TAS | Brain (GO term level: 8) | 15705863 |
GO:0030900 | forebrain development | TAS | Brain (GO term level: 8) | 15705863 |
GO:0001708 | cell fate specification | IEA | | - |
GO:0009953 | dorsal/ventral pattern formation | IEA | | - |
GO:0009952 | anterior/posterior pattern formation | IEA | | - |
GO:0009887 | organ morphogenesis | IEA | | - |
GO:0008589 | regulation of smoothened signaling pathway | TAS | | 15705863 |
GO:0007275 | multicellular organismal development | IEA | | - |
GO:0042472 | inner ear morphogenesis | IEA | | - |
GO:0042706 | eye photoreceptor cell fate commitment | IEA | | - |
GO:0040036 | regulation of fibroblast growth factor receptor signaling pathway | TAS | | 15705863 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0030426 | growth cone | IDA | axon, dendrite (GO term level: 5) | 16267555 |
GO:0005634 | nucleus | IEA | | - |
GO:0005737 | cytoplasm | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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