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GeneID |
5027
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Symbol |
P2RX7
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Synonyms |
MGC20089|P2X7
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Description |
purinergic receptor P2X, ligand-gated ion channel, 7 |
See related |
HGNC:8537|MIM:602566|Ensembl:ENSG00000089041|HPRD:03977| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
12q24 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
Top 10 negatively co-expressed genes | |
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005102 | receptor binding | ISS | Neurotransmitter (GO term level: 4) | 17785580 |
GO:0001530 | lipopolysaccharide binding | ISS | | - |
GO:0001614 | purinergic nucleotide receptor activity | IPI | | 9038151 |
GO:0004872 | receptor activity | IEA | | - |
GO:0004931 | ATP-gated cation channel activity | IDA | | 9038151 |
GO:0004931 | ATP-gated cation channel activity | IEA | | - |
GO:0005524 | ATP binding | IEA | | - |
GO:0005216 | ion channel activity | IEA | | - |
GO:0042803 | protein homodimerization activity | NAS | | 17895406 |
GO:0046982 | protein heterodimerization activity | ISS | | 17785580 |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0002028 | regulation of sodium ion transport | ISS | | 17785580 |
GO:0010524 | positive regulation of calcium ion transport into cytosol | IDA | | 9038151 |
GO:0007166 | cell surface receptor linked signal transduction | ISS | | - |
GO:0006811 | ion transport | IEA | | - |
GO:0006812 | cation transport | IEA | | - |
GO:0042981 | regulation of apoptosis | ISS | | - |
GO:0033198 | response to ATP | IDA | | 9038151 |
GO:0030501 | positive regulation of bone mineralization | IEA | | - |
GO:0030501 | positive regulation of bone mineralization | ISS | | - |
GO:0019233 | sensory perception of pain | ISS | | - |
GO:0032060 | bleb formation | ISS | | - |
GO:0043409 | negative regulation of MAPKKK cascade | ISS | | - |
GO:0045779 | negative regulation of bone resorption | IEA | | - |
GO:0045779 | negative regulation of bone resorption | ISS | | - |
GO:0045919 | positive regulation of cytolysis | ISS | | - |
GO:0046931 | pore complex biogenesis | IDA | | 9038151 |
GO:0050718 | positive regulation of interleukin-1 beta secretion | IDA | | 17036048 |18089587 |
GO:0051495 | positive regulation of cytoskeleton organization | ISS | | - |
GO:0051709 | regulation of killing of cells of another organism | NAS | | 17785580 |
GO:0051899 | membrane depolarization | IDA | | 9038151 |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005737 | cytoplasm | ISS | | - |
GO:0016020 | membrane | IEA | | - |
GO:0016021 | integral to membrane | IEA | | - |
GO:0005886 | plasma membrane | ISS | | 17785580 |
GO:0005887 | integral to plasma membrane | IC | | 9038151 |
GO:0005887 | integral to plasma membrane | IEA | | - |
GO:0032059 | bleb | ISS | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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