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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: PAX3

Summary

GeneID

5077

Symbol

PAX3

Synonyms

CDHS|HUP2|MGC120381|MGC120382|MGC120383|MGC120384|MGC134778|WS1

Description

paired box 3

Locus tag

Gene type

protein-coding

Map location

2q35-q37|2q35

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00916

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.01016

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

IEA

GO:0003700

transcription factor activity

TAS

9500554

GO:0005515

protein binding

IPI

11029584

GO:0043565

sequence-specific DNA binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006366

transcription from RNA polymerase II promoter

TAS

9500554

GO:0009887

organ morphogenesis

TAS

8447316

GO:0007605

sensory perception of sound

TAS

9500554

GO:0006915

apoptosis

TAS

10871843

GO:0007275

multicellular organismal development

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CNR1	CANN6 \| CB-R \| CB1 \| CB1A \| CB1K5 \| CB1R \| CNR	cannabinoid receptor 1 (brain)	An unspecified isoform of PAX3 interacts with the CNR1 promoter.	BIND	15688035
DAXX	BING2 \| DAP6 \| EAP1 \| MGC126245 \| MGC126246	death-domain associated protein	-	HPRD,BioGRID	10393185
IPO13	IMP13 \| KAP13 \| KIAA0724 \| RANBP13	importin 13	Kap13 interacts with Pax3.	BIND	15143176
IPO13	IMP13 \| KAP13 \| KIAA0724 \| RANBP13	importin 13	Reconstituted Complex	BioGRID	15143176
MEOX1	MOX1	mesenchyme homeobox 1	Reconstituted Complex Two-hybrid	BioGRID	11423130
MEOX2	GAX \| MOX2	mesenchyme homeobox 2	Reconstituted Complex Two-hybrid	BioGRID	11423130
MSX1	HOX7 \| HYD1	msh homeobox 1	Reconstituted Complex	BioGRID	10529415
POU3F2	BRN2 \| OCT7 \| OTF7 \| POUF3	POU class 3 homeobox 2	Brn-2 interacts with Pax3.	BIND	11029584
SOX10	DOM \| MGC15649 \| WS2E \| WS4	SRY (sex determining region Y)-box 10	Pax3 interacts with Sox10.	BIND	11029584
SOX10	DOM \| MGC15649 \| WS2E \| WS4	SRY (sex determining region Y)-box 10	-	HPRD,BioGRID	10942418 \|12668617
TBP	GTF2D \| GTF2D1 \| MGC117320 \| MGC126054 \| MGC126055 \| SCA17 \| TFIID	TATA box binding protein	Reconstituted Complex	BioGRID	10359315

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
BIOCARTA_PML_PATHWAY	17	12	All SZGR genes in this pathway
PID_RB_1PATHWAY	65	46	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	485	293	All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP	146	99	All SZGR genes in this pathway
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_25	15	6	All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK	1652	1023	All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK	1442	892	All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS	1038	678	All SZGR genes in this pathway
BENPORATH_EED_TARGETS	1062	725	All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3	1118	744	All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS	652	441	All SZGR genes in this pathway
TSENG_IRS1_TARGETS_DN	135	88	All SZGR genes in this pathway
TSENG_ADIPOGENIC_POTENTIAL_DN	46	28	All SZGR genes in this pathway
SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_DN	7	5	All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP	323	240	All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_DN	49	34	All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	1069	729	All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3	349	234	All SZGR genes in this pathway
DANG_MYC_TARGETS_UP	143	100	All SZGR genes in this pathway
DANG_BOUND_BY_MYC	1103	714	All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3	341	243	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A	898	516	All SZGR genes in this pathway
WANG_MLL_TARGETS	289	188	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	612	618	1A	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-1/206	91	98	1A,m8	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
				hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-144	604	610	m8	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-145	298	304	1A	hsa-miR-145	GUCCAGUUUUCCCAGGAAUCCCUU
miR-199	296	303	1A,m8	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	296	303	1A,m8	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-217	1239	1245	1A	hsa-miR-217	UACUGCAUCAGGAACUGAUUGGAU
miR-25/32/92/363/367	599	606	1A,m8	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
miR-30-5p	928	934	1A	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
				hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-380-5p	1194	1200	1A	hsa-miR-380-5p	UGGUUGACCAUAGAACAUGCGC
miR-380-5p	1194	1200	1A	hsa-miR-563	AGGUUGACAUACGUUUCCC
miR-409-3p	90	96	m8	hsa-miR-409-3p	CGAAUGUUGCUCGGUGAACCCCU
miR-485-5p	1189	1196	1A,m8	hsa-miR-485-5p	AGAGGCUGGCCGUGAUGAAUUC
miR-496	1228	1235	1A,m8	hsa-miR-496	AUUACAUGGCCAAUCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.