Gene Page: PAX5

Summary
GeneID  5079
Symbol  PAX5
Synonyms  BSAP
Description  paired box 5
See related  HGNC:8619|MIM:167414|Ensembl:ENSG00000196092|HPRD:01334|
Locus tag  -
Gene type  protein-coding
Map location  9p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MCM50.950.75
CDC45L0.940.68
MCM20.940.81
DTL0.940.74
TIMELESS0.940.69
CCNB10.940.79
RAD510.940.72
AC087645.20.940.69
BIRC50.930.69
GINS20.930.69
Top 10 negatively co-expressed genes
MT-CO2-0.50-0.75
AF347015.33-0.50-0.75
AF347015.27-0.50-0.74
AF347015.31-0.49-0.73
MT-CYB-0.49-0.76
AF347015.8-0.49-0.76
AF347015.15-0.48-0.76
HLA-F-0.47-0.63
AF347015.2-0.46-0.76
AF347015.26-0.46-0.75
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0003700transcription factor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentIEAneurite (GO term level: 5)-
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006366transcription from RNA polymerase II promoterTAS10524622 
GO:0007283spermatogenesisIEA-
GO:0009887organ morphogenesisTAS10524622 
GO:0006959humoral immune responseTAS10524629 
GO:0007275multicellular organismal developmentIEA-
GO:0007275multicellular organismal developmentTAS10524629 
GO:0030154cell differentiationIEA-
GO:0051573negative regulation of histone H3-K9 methylationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CREBBPCBP | KAT3A | RSTSCREB binding proteinCBP interacts with Pax5.BIND11799127 
DAXXBING2 | DAP6 | EAP1 | MGC126245 | MGC126246death-domain associated protein-HPRD,BioGRID11799127 
Pax5 interacts with Daxx.BIND11799127 
ETS1ETS-1 | EWSR2 | FLJ10768v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)-HPRD10022910 
ID3HEIR-1 | bHLHb25inhibitor of DNA binding 3, dominant negative helix-loop-helix protein-HPRD,BioGRID12054881 
KPNA1IPOA5 | NPI-1 | RCH2 | SRP1karyopherin alpha 1 (importin alpha 5)-HPRD10748034 
KPNA2IPOA1 | QIP2 | RCH1 | SRP1alphakaryopherin alpha 2 (RAG cohort 1, importin alpha 1)-HPRD10748034 
MYBCmyb | c-myb | c-myb_CDS | efgv-myb myeloblastosis viral oncogene homolog (avian)-HPRD,BioGRID11781241 
RUNX1AML1 | AML1-EVI-1 | AMLCR1 | CBFA2 | EVI-1 | PEBP2aBrunt-related transcription factor 1-HPRD,BioGRID10455134 
TLE4BCE-1 | BCE1 | E(spI) | ESG | ESG4 | GRG4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)-HPRD,BioGRID12153506 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_CMYB_PATHWAY 8461All SZGR genes in this pathway
DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP 5938All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN 349157All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_UP 3019All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
RIZ_ERYTHROID_DIFFERENTIATION_12HR 4335All SZGR genes in this pathway
KLEIN_TARGETS_OF_BCR_ABL1_FUSION 4534All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER 8864All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN 357212All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_9 1913All SZGR genes in this pathway
HADDAD_B_LYMPHOCYTE_PROGENITOR 293193All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD2_UP 4532All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_DN 245144All SZGR genes in this pathway
SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 419273All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
HUANG_FOXA2_TARGETS_UP 4528All SZGR genes in this pathway
HOQUE_METHYLATED_IN_CANCER 5645All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP 323240All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 317177All SZGR genes in this pathway
MIKKELSEN_MCV6_ICP_WITH_H3K27ME3 7446All SZGR genes in this pathway
MIKKELSEN_MEF_ICP_WITH_H3K27ME3 206108All SZGR genes in this pathway
MIKKELSEN_IPS_ICP_WITH_H3K27ME3 5432All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_MS_DN 4624All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 13785All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D 280158All SZGR genes in this pathway
DUAN_PRDM5_TARGETS 7952All SZGR genes in this pathway
LIU_TOPBP1_TARGETS 168All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4963833901A,m8hsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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