Gene Page: TTRAP

Summary
GeneID  51567
Symbol  TTRAP
Synonyms  AD022|EAP2|MGC111021|MGC9099|dJ30M3.3
Description  TRAF and TNF receptor associated protein
See related  HGNC:17768|MIM:605764|Ensembl:ENSG00000111802|HPRD:05771|
Locus tag  RP1-30M3.3
Gene type  protein-coding
Map location  6p22.3-p22.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003714transcription corepressor activityTAS10764746 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007166cell surface receptor linked signal transductionTAS10764746 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD40Bp50 | CDW40 | MGC9013 | TNFRSF5 | p50CD40 molecule, TNF receptor superfamily member 5-HPRD,BioGRID10764746 
ETS1ETS-1 | EWSR2 | FLJ10768v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)EAPII interacts with ETS1.BIND12743594 
-HPRD,BioGRID12743594 
EAPII interacts with p42-ETS1.BIND12743594 
ETS2ETS2IT1v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)ETS2 interacts with EAPII.BIND12743594 
FLI1EWSR2 | SIC-1Friend leukemia virus integration 1FLI1 interacts with EAPII.BIND12743594 
SUMO1DAP-1 | GMP1 | OFC10 | PIC1 | SENP2 | SMT3 | SMT3C | SMT3H3 | SUMO-1 | UBL1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)SUMO-1 interacts with TTRAP.BIND14609633 
Two-hybridBioGRID14609633 
TNFRSF1BCD120b | TBPII | TNF-R-II | TNF-R75 | TNFBR | TNFR1B | TNFR2 | TNFR80 | p75 | p75TNFRtumor necrosis factor receptor superfamily, member 1B-HPRD,BioGRID10764746 
TNFRSF8CD30 | D1S166E | KI-1tumor necrosis factor receptor superfamily, member 8-HPRD,BioGRID10764746 
TRAF2MGC:45012 | TRAP | TRAP3TNF receptor-associated factor 2-HPRD,BioGRID10764746 
TRAF3CAP-1 | CD40bp | CRAF1 | LAP1TNF receptor-associated factor 3Affinity Capture-WesternBioGRID10764746 
TRAF5MGC:39780 | RNF84TNF receptor-associated factor 5-HPRD,BioGRID10764746 
TRAF6MGC:3310 | RNF85TNF receptor-associated factor 6-HPRD,BioGRID10764746 
UBE2IC358B7.1 | P18 | UBC9ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)Two-hybridBioGRID14609633 
Ubc9 interacts with TTRAP.BIND14609633 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_CD40_PATHWAY 3126All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_DN 310188All SZGR genes in this pathway
PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP 5236All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
GRASEMANN_RETINOBLASTOMA_WITH_6P_AMPLIFICATION 1414All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN 7345All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN 172107All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP 570339All SZGR genes in this pathway


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