|
GeneID |
5198
|
Symbol |
PFAS
|
Synonyms |
FGAMS|FGARAT|KIAA0361|PURL
|
Description |
phosphoribosylformylglycinamidine synthase |
See related |
HGNC:8863|MIM:602133|Ensembl:ENSG00000178921|HPRD:09072| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
17p13.1 |
|
|
|
Gene set name |
Method of gene set |
Evidence |
Info |
GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 2 | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.0044 | |
|
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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|
Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
SLC25A4 | 0.90 | 0.90 | | |
PKM2 | 0.86 | 0.87 | | |
TMEM111 | 0.86 | 0.85 | | |
PPT1 | 0.85 | 0.84 | | |
GHITM | 0.85 | 0.90 | | |
FOXRED1 | 0.85 | 0.80 | | |
SNURF | 0.85 | 0.89 | | |
NEU1 | 0.84 | 0.83 | | |
PET112L | 0.84 | 0.85 | | |
PEX19 | 0.84 | 0.83 | | |
Top 10 negatively co-expressed genes | AC010300.1 | -0.48 | -0.57 | | |
AF347015.18 | -0.46 | -0.33 | | |
C10orf108 | -0.44 | -0.46 | | |
AC005921.3 | -0.44 | -0.54 | | |
IL3RA | -0.41 | -0.59 | | |
HSP90AB4P | -0.41 | -0.46 | | |
AC100783.1 | -0.40 | -0.39 | | |
NSBP1 | -0.40 | -0.38 | | |
EIF5B | -0.40 | -0.42 | | |
ZNF814 | -0.39 | -0.47 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0004642 | phosphoribosylformylglycinamidine synthase activity | EXP | glutamate (GO term level: 6) | 8110788 |
GO:0004642 | phosphoribosylformylglycinamidine synthase activity | IDA | glutamate (GO term level: 6) | 10548741 |
GO:0000166 | nucleotide binding | IEA | | - |
GO:0005515 | protein binding | IPI | | 17353931 |
GO:0005524 | ATP binding | IEA | | - |
GO:0016874 | ligase activity | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0006189 | 'de novo' IMP biosynthetic process | NAS | | 10548741 |
GO:0006164 | purine nucleotide biosynthetic process | IEA | | - |
GO:0006541 | glutamine metabolic process | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005829 | cytosol | EXP | | 8110788 |
GO:0005737 | cytoplasm | NAS | | - |
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