Gene Page: PFDN1

Summary
GeneID  5201
Symbol  PFDN1
Synonyms  PDF|PFD1
Description  prefoldin subunit 1
See related  HGNC:8866|MIM:604897|Ensembl:ENSG00000113068|HPRD:05357|
Locus tag  -
Gene type  protein-coding
Map location  5q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS8744932 
GO:0051082unfolded protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006457protein foldingIEA-
GO:0007049cell cycleTAS8744932 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIDA18029348 
GO:0005886plasma membraneIDA18029348 
GO:0016272prefoldin complexIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTA1ACTA | ASMA | CFTD | CFTD1 | CFTDM | MPFD | NEM1 | NEM2 | NEM3actin, alpha 1, skeletal muscleReconstituted ComplexBioGRID14634002 
ACTBPS1TP5BP1actin, beta-HPRD11535601 
C1orf103FLJ11269 | RIF1 | RP11-96K19.1chromosome 1 open reading frame 103Two-hybridBioGRID16169070 
GIT1-G protein-coupled receptor kinase interacting ArfGAP 1Two-hybridBioGRID16169070 
GPRASP1GASP | GASP1 | KIAA0443G protein-coupled receptor associated sorting protein 1Two-hybridBioGRID16169070 
HAP1HAP2 | HIP5 | HLP | hHLP1huntingtin-associated protein 1Two-hybridBioGRID16169070 
HIP1ILWEQ | MGC126506huntingtin interacting protein 1Two-hybridBioGRID16169070 
IMMTDKFZp779P1653 | HMP | MGC111146 | P87 | P87/89 | P89 | PIG4 | PIG52inner membrane protein, mitochondrial (mitofilin)Two-hybridBioGRID16169070 
KIAA1377-KIAA1377Two-hybridBioGRID16169070 
MED313110004H13Rik | CGI-125 | FLJ27436 | FLJ36714 | Soh1mediator complex subunit 31Two-hybridBioGRID16169070 
PSME1IFI5111 | MGC8628 | PA28A | PA28alpha | REGalphaproteasome (prosome, macropain) activator subunit 1 (PA28 alpha)Two-hybridBioGRID16169070 
RPLP1FLJ27448 | MGC5215 | P1 | RPP1ribosomal protein, large, P1Two-hybridBioGRID16169070 
TUBA1AB-ALPHA-1 | FLJ25113 | LIS3 | TUBA3tubulin, alpha 1aReconstituted ComplexBioGRID14634002 
WDR8FLJ20430 | MGC99569WD repeat domain 8Affinity Capture-MSBioGRID17353931 
YEATS44930573H17Rik | B230215M10Rik | GAS41 | NUBI-1 | YAF9YEATS domain containing 4Two-hybridBioGRID11521196 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC 2815All SZGR genes in this pathway
REACTOME_PROTEIN_FOLDING 5330All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
WANG_CLIM2_TARGETS_DN 186114All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP 11966All SZGR genes in this pathway
PEART_HDAC_PROLIFERATION_CLUSTER_DN 7657All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
KIM_ALL_DISORDERS_DURATION_CORR_DN 14690All SZGR genes in this pathway


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