Gene Page

Gene Page: PFTK1

Summary

GeneID

5218

Symbol

PFTK1

Synonyms

KIAA0834|PFTAIRE1

Description

PFTAIRE protein kinase 1

Locus tag

Gene type

protein-coding

Map location

7q21-q22

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0583

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

ATP5B

0.91

UQCRC2

0.89

0.88

SRPRB

0.89

0.85

PSMA1

0.88

0.84

MRPL37

0.87

0.81

HSPA8

0.86

0.85

PSMC2

0.86

0.80

SARS

0.85

0.80

RRAGA

0.85

0.78

RAN

0.84

0.83

Top 10 negatively co-expressed genes

AF347015.18

-0.69

-0.58

AF347015.8

-0.67

-0.50

AF347015.26

-0.66

-0.51

AF347015.2

-0.66

-0.49

AF347015.21

-0.65

-0.45

MT-CO2

-0.64

-0.47

AF347015.33

-0.64

-0.50

AF347015.15

-0.63

-0.49

MT-CYB

-0.62

-0.48

MT-ATP8

-0.62

-0.49

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004693

cyclin-dependent protein kinase activity

IEA

neuron (GO term level: 8)

GO:0000166

nucleotide binding

IEA

GO:0005515

protein binding

IPI

16775625 |17353931 |17517622

GO:0005524

ATP binding

IEA

GO:0016740

transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006468

protein amino acid phosphorylation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

IEA

GO:0005634

nucleus

TAS

9202329

GO:0005737

cytoplasm

TAS

9202329

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
IGHA2	-	immunoglobulin heavy constant alpha 2 (A2m marker)	Affinity Capture-MS	BioGRID	17353931
SEPT8	KIAA0202 \| SEP2	septin 8	-	HPRD,BioGRID	12098780

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	1815	1822	1A,m8	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
				hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-103/107	2970	2977	1A,m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	2970	2977	1A,m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-132/212	676	682	m8	hsa-miR-212^SZ	UAACAGUCUCCAGUCACGGCC
miR-132/212	676	682	m8	hsa-miR-132^brain	UAACAGUCUACAGCCAUGGUCG
miR-145	2450	2456	1A	hsa-miR-145	GUCCAGUUUUCCCAGGAAUCCCUU
miR-199	2449	2455	1A	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	2449	2455	1A	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-208	359	365	1A	hsa-miR-208	AUAAGACGAGCAAAAAGCUUGU
miR-26	416	422	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	416	422	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-27	2872	2878	1A	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	2872	2878	1A	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-33	1114	1120	m8	hsa-miR-33	GUGCAUUGUAGUUGCAUUG
miR-33	1114	1120	m8	hsa-miR-33b	GUGCAUUGCUGUUGCAUUGCA
miR-339	733	740	1A,m8	hsa-miR-339	UCCCUGUCCUCCAGGAGCUCA
miR-409-3p	1028	1034	m8	hsa-miR-409-3p	CGAAUGUUGCUCGGUGAACCCCU
miR-455	3140	3147	1A,m8	hsa-miR-455	UAUGUGCCUUUGGACUACAUCG
miR-499	359	365	1A	hsa-miR-499	UUAAGACUUGCAGUGAUGUUUAA
miR-543	2454	2460	m8	hsa-miR-543	AAACAUUCGCGGUGCACUUCU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.