Gene Page

Gene Page: ATP6V1E1

Summary

GeneID

529

Symbol

ATP6V1E1

Synonyms

ATP6E|ATP6E2|ATP6V1E|P31|Vma4

Description

ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1

Locus tag

Gene type

protein-coding

Map location

22pter-q11.2|22q11.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.031

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0044

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

14667819

GO:0016787

hydrolase activity

IEA

GO:0008553

hydrogen-exporting ATPase activity, phosphorylative mechanism

IEA

GO:0046961

hydrogen ion transporting ATPase activity, rotational mechanism

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006811

ion transport

IEA

GO:0015992

proton transport

TAS

8250920

GO:0015991

ATP hydrolysis coupled proton transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

IEA

GO:0005739

mitochondrion

IEA

GO:0016469

proton-transporting two-sector ATPase complex

TAS

8250920

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ALDOA	ALDA \| MGC10942 \| MGC17716 \| MGC17767	aldolase A, fructose-bisphosphate	-	HPRD,BioGRID	11399750
ALDOB	-	aldolase B, fructose-bisphosphate	-	HPRD,BioGRID	11399750
ALDOC	ALDC	aldolase C, fructose-bisphosphate	Two-hybrid	BioGRID	11399750
ATP6V1G1	ATP6G \| ATP6G1 \| ATP6GL \| ATP6J \| DKFZp547P234 \| Vma10	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	Two-hybrid	BioGRID	16169070
ATP6V1G2	ATP6G \| ATP6G2 \| NG38 \| VMA10	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2	Two-hybrid	BioGRID	14667819
ATP6V1H	CGI-11 \| MSTP042 \| NBP1 \| SFD \| SFDalpha \| SFDbeta \| VMA13	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	-	HPRD,BioGRID	12163484
SLC9A3R1	EBP50 \| NHERF \| NHERF1 \| NPHLOP2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	-	HPRD	10748165
SOS1	GF1 \| GGF1 \| GINGF \| HGF \| NS4	son of sevenless homolog 1 (Drosophila)	-	HPRD	11560919
XRCC6	CTC75 \| CTCBF \| G22P1 \| KU70 \| ML8 \| TLAA	X-ray repair complementing defective repair in Chinese hamster cells 6	Two-hybrid	BioGRID	16169070

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-23	448	454	m8	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	448	454	m8	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-323	448	454	1A	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.