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| GeneID |
5413
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| Symbol |
SEPT5
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| Synonyms |
CDCREL|CDCREL-1|CDCREL1|H5|PNUTL1
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| Description |
septin 5 |
| See related |
HGNC:9164|MIM:602724|Ensembl:ENSG00000184702|HPRD:04100| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
22q11.21 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_I | genome scan meta-analysis | Psr: 0.031 | | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 4 | | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.3501 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| HRSP12 | 0.89 | 0.89 | | |
| BBOX1 | 0.88 | 0.93 | | |
| SLC15A2 | 0.86 | 0.87 | | |
| DBX2 | 0.84 | 0.82 | | |
| SLCO1C1 | 0.83 | 0.90 | | |
| HSD17B6 | 0.83 | 0.91 | | |
| S1PR1 | 0.83 | 0.85 | | |
| GLUD1 | 0.82 | 0.78 | | |
| PLSCR4 | 0.82 | 0.76 | | |
| CD302 | 0.81 | 0.79 | | |
Top 10 negatively co-expressed genes | | FAM131B | -0.64 | -0.76 | | |
| KIF3C | -0.63 | -0.74 | | |
| NMNAT2 | -0.63 | -0.74 | | |
| NEURL4 | -0.63 | -0.75 | | |
| RTF1 | -0.63 | -0.74 | | |
| C6orf168 | -0.62 | -0.75 | | |
| RAB35 | -0.62 | -0.76 | | |
| MTMR4 | -0.62 | -0.75 | | |
| PREP | -0.62 | -0.73 | | |
| EIF4ENIF1 | -0.62 | -0.74 | | |
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| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0000166 | nucleotide binding | IEA | | - |
| GO:0003924 | GTPase activity | TAS | | 9385360 |
| GO:0005515 | protein binding | IEA | | - |
| GO:0005515 | protein binding | IPI | | 10321247 |
| GO:0005515 | protein binding | ISS | | - |
| GO:0005525 | GTP binding | IEA | | - |
| GO:0005198 | structural molecule activity | TAS | | 9611266 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0016080 | synaptic vesicle targeting | TAS | Synap (GO term level: 10) | 10321247 |
| GO:0000910 | cytokinesis | TAS | | 9611266 |
| GO:0007049 | cell cycle | IEA | | - |
| GO:0017157 | regulation of exocytosis | IMP | | 10321247 |
| GO:0017157 | regulation of exocytosis | ISS | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0008021 | synaptic vesicle | IDA | Synap, Neurotransmitter (GO term level: 12) | 10321247 |
| GO:0008021 | synaptic vesicle | ISS | Synap, Neurotransmitter (GO term level: 12) | - |
| GO:0019717 | synaptosome | IEA | Synap, Brain (GO term level: 7) | - |
| GO:0005886 | plasma membrane | IDA | | 10321247 |
| GO:0005886 | plasma membrane | ISS | | - |
| GO:0031105 | septin complex | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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