Gene Page: PON1

Summary
GeneID  5444
Symbol  PON1
Synonyms  ESA|PON
Description  paraoxonase 1
See related  HGNC:9204|MIM:168820|Ensembl:ENSG00000005421|HPRD:01351|
Locus tag  -
Gene type  protein-coding
Map location  7q21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
BDH10.880.91
AC068580.30.870.89
TAPBP0.870.90
TUBG20.860.87
CTSD0.860.87
CEND10.860.87
DHRS110.850.85
C19orf660.850.87
ZFYVE280.850.87
PNPO0.850.86
Top 10 negatively co-expressed genes
TUBB2B-0.55-0.48
RBMX2-0.55-0.58
KIAA1949-0.55-0.37
RPS8-0.54-0.60
ZNF300-0.53-0.33
TMSB15A-0.53-0.53
VASH2-0.53-0.31
FNBP1L-0.53-0.30
RPL5-0.53-0.51
HDAC2-0.53-0.31
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004063aryldialkylphosphatase activityIEA-
GO:0004064arylesterase activityNAS1673382 
GO:0005319lipid transporter activityIEA-
GO:0016787hydrolase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008203cholesterol metabolic processIEA-
GO:0009605response to external stimulusNAS1657140 
GO:0009636response to toxinIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonIDA18029348 
GO:0005576extracellular regionNAS14718574 
GO:0005737cytoplasmIDA18029348 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ALBDKFZp779N1935 | PRO0883 | PRO0903 | PRO1341albumin-HPRD6324579 
CLUAAG4 | APOJ | CLI | KUB1 | MGC24903 | SGP-2 | SGP2 | SP-40 | TRPM-2 | TRPM2clusterin-HPRD8292612 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
NIKOLSKY_BREAST_CANCER_7Q21_Q22_AMPLICON 7633All SZGR genes in this pathway
LEE_LIVER_CANCER_CIPROFIBRATE_DN 6643All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_DN 185111All SZGR genes in this pathway
LEE_LIVER_CANCER_DENA_DN 7445All SZGR genes in this pathway
JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN 4331All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
KEEN_RESPONSE_TO_ROSIGLITAZONE_DN 10668All SZGR genes in this pathway
MCDOWELL_ACUTE_LUNG_INJURY_DN 4833All SZGR genes in this pathway
YEGNASUBRAMANIAN_PROSTATE_CANCER 12860All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
LEE_EARLY_T_LYMPHOCYTE_UP 10759All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 196124All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_DN 5132All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway


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