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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: DGCR8

Summary

GeneID

54487

Symbol

DGCR8

Synonyms

C22orf12|DGCRK6|Gy1

Description

DiGeorge syndrome critical region gene 8

Locus tag

Gene type

protein-coding

Map location

22q11.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.031

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003725

double-stranded RNA binding

IEA

GO:0005515

protein binding

IPI

15574589

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0031053

primary microRNA processing

IDA

15531877 |15574589

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

IDA

15574589

GO:0005737

cytoplasm

IDA

11256614

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
RNASEN	DROSHA \| ETOHI2 \| HSA242976 \| RANSE3L \| RN3 \| RNASE3L	ribonuclease type III, nuclear	Drosha interacts with DGCR8 to form the Microprocessor complex.	BIND	15531877
RNASEN	DROSHA \| ETOHI2 \| HSA242976 \| RANSE3L \| RN3 \| RNASE3L	ribonuclease type III, nuclear	hDrosha interacts with DGCR8.	BIND	15589161

Pathway annotation

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-205	314	320	m8	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-208	720	726	1A	hsa-miR-208	AUAAGACGAGCAAAAAGCUUGU
miR-499	719	726	1A,m8	hsa-miR-499	UUAAGACUUGCAGUGAUGUUUAA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.