Gene Page: POU1F1

Summary
GeneID  5449
Symbol  POU1F1
Synonyms  GHF-1|PIT1|Pit-1
Description  POU class 1 homeobox 1
See related  HGNC:9210|MIM:173110|Ensembl:ENSG00000064835|HPRD:01409|
Locus tag  -
Gene type  protein-coding
Map location  3p11
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.04047 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04359 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
UBE2V20.920.91
ZC3H150.920.91
DNAJA20.910.89
DNM1L0.890.87
UCHL50.880.88
CUL20.880.86
MORF4L20.880.86
BTBD100.880.86
UBE2K0.880.88
PPP2CA0.870.86
Top 10 negatively co-expressed genes
MT-CO2-0.66-0.60
AF347015.2-0.66-0.58
FXYD1-0.64-0.61
AF347015.26-0.64-0.56
AF347015.8-0.64-0.58
AF347015.31-0.63-0.59
AF347015.33-0.63-0.58
MT-CYB-0.63-0.57
AF347015.21-0.62-0.50
HIGD1B-0.62-0.58
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS1487156 |9482665 
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006366transcription from RNA polymerase II promoterTAS1487156 
GO:0009887organ morphogenesisTAS9482665 
GO:0008285negative regulation of cell proliferationTAS9392392 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GATA2MGC2306 | NFE1BGATA binding protein 2-HPRD,BioGRID10367888 
JUNAP-1 | AP1 | c-Junjun oncogene-HPRD,BioGRID8663380 
NR1I2BXR | ONR1 | PAR | PAR1 | PAR2 | PARq | PRR | PXR | SAR | SXRnuclear receptor subfamily 1, group I, member 2-HPRD,BioGRID11891224 
NR1I3CAR | CAR1 | MB67 | MGC150433 | MGC97144 | MGC97209nuclear receptor subfamily 1, group I, member 3-HPRD,BioGRID11891224 
NR3C1GCCR | GCR | GR | GRLnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)-HPRD,BioGRID9426156 
PITX1BFT | POTX | PTX1paired-like homeodomain 1-HPRD,BioGRID8755540 
PPARAMGC2237 | MGC2452 | NR1C1 | PPAR | hPPARperoxisome proliferator-activated receptor alphaReconstituted ComplexBioGRID11891224 
PPARGNR1C3 | PPARG1 | PPARG2 | PPARgammaperoxisome proliferator-activated receptor gammaReconstituted ComplexBioGRID11891224 
VDRNR1I1vitamin D (1,25- dihydroxyvitamin D3) receptorReconstituted ComplexBioGRID11891224 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_REG_GR_PATHWAY 8260All SZGR genes in this pathway
HEIDENBLAD_AMPLIFIED_IN_SOFT_TISSUE_CANCER 137All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PARK_HSC_AND_MULTIPOTENT_PROGENITORS 5033All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_UP 180125All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
MATZUK_CENTRAL_FOR_FEMALE_FERTILITY 2925All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_UP 6144All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_A 182108All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


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