Gene Page: RRN3

Summary
GeneID  54700
Symbol  RRN3
Synonyms  DKFZp566E104|MGC104238|TIFIA
Description  RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
See related  HGNC:30346|MIM:605121|Ensembl:ENSG00000085721|HPRD:12004|
Locus tag  -
Gene type  protein-coding
Map location  16p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003701RNA polymerase I transcription factor activityTAS10758157 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006360transcription from RNA polymerase I promoterTAS10758157 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTBPS1TP5BP1actin, betaTIF-IA interacts with actin.BIND15558034 
CCNE1CCNEcyclin E1Reconstituted ComplexBioGRID15004009 
CDK2p33(CDK2)cyclin-dependent kinase 2Reconstituted ComplexBioGRID15004009 
EIF3EIPEIF3S11 | EIF3S6IP | HSPC021 | HSPC025 | MSTP005eukaryotic translation initiation factor 3, subunit E interacting proteinTIF-IA interacts with PAF67. This interaction was modeled on a demonstrated interaction between human TIF-IA and PAF67 from an unspecified species.BIND12393749 
MYO1CFLJ23903 | MMI-beta | MMIb | NMI | myr2myosin ICNMI interacts with TIF-IA.BIND15558034 
POLR1ADKFZp586M0122 | FLJ21915 | MGC87965 | RPA1 | RPO1-4polymerase (RNA) I polypeptide A, 194kDa-HPRD,BioGRID11250903 
TIF-IA interacts with RPA43. This interaction was modeled on a demonstrated interaction between human TIF-IA and mouse RPA43.BIND12393749 
POLR1BFLJ10816 | FLJ21921 | MGC131780 | RPA135 | RPA2 | Rpo1-2polymerase (RNA) I polypeptide B, 128kDaPol I interacts with TIF-IA.BIND15558034 
-HPRD11250903 
PPP2R2AB55-ALPHA | B55A | FLJ26613 | MGC52248 | PR52A | PR55Aprotein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoformReconstituted ComplexBioGRID15004009 
RIBIN-rRNA promoter binding proteinTIF-IA interacts with rDNA.BIND15558034 
TAF1AMGC:17061 | RAFI48 | SL1 | TAFI48TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa-HPRD,BioGRID11250903 
TAF1BMGC:9349 | RAF1B | RAFI63 | SL1 | TAFI63TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa-HPRD,BioGRID11250903 
TIF-IA interacts with TAFI68. This interaction was modeled on a demonstrated interaction between human TIF-IA and TAFI68 from an unspecified species.BIND12393749 
TAF1CMGC:39976 | SL1 | TAFI110 | TAFI95TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa-HPRD,BioGRID11250903 
TIF-IA interacts with TAFI95. This interaction was modeled on a demonstrated interaction between human TIF-IA and TAFI95 from an unspecified species.BIND12393749 
TBPGTF2D | GTF2D1 | MGC117320 | MGC126054 | MGC126055 | SCA17 | TFIIDTATA box binding proteinAffinity Capture-WesternBioGRID11250903 
UBTFNOR-90 | UBFupstream binding transcription factor, RNA polymerase IAffinity Capture-WesternBioGRID11250903 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_MTOR_4PATHWAY 6955All SZGR genes in this pathway
REACTOME_RNA_POL_I_TRANSCRIPTION 8964All SZGR genes in this pathway
REACTOME_TRANSCRIPTION 210127All SZGR genes in this pathway
REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 12280All SZGR genes in this pathway
REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION 2514All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
BIDUS_METASTASIS_UP 214134All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
RAMALHO_STEMNESS_UP 206118All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
LIN_NPAS4_TARGETS_UP 163100All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway


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