Gene Page: PPP2R2C

Summary
GeneID  5522
Symbol  PPP2R2C
Synonyms  B55-GAMMA|IMYPNO|IMYPNO1|MGC33570|PR52|PR55G
Description  protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform
See related  HGNC:9306|MIM:605997|Ensembl:ENSG00000074211|HPRD:09345|
Locus tag  -
Gene type  protein-coding
Map location  4p16.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.432 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FXYD70.560.56
YPEL30.560.57
RFPL20.560.57
YPEL40.550.59
P4HTM0.540.57
HMOX20.540.55
MPI0.530.53
MRPS250.530.55
ADC0.520.55
C6orf1360.520.54
Top 10 negatively co-expressed genes
AF347015.18-0.31-0.16
AF347015.21-0.28-0.16
MT-ATP8-0.27-0.12
ANP32C-0.25-0.28
RP11-3P17.1-0.25-0.26
AF347015.2-0.24-0.09
IL32-0.24-0.20
EDN1-0.24-0.06
CD248-0.24-0.23
FAM159B-0.24-0.30
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008601protein phosphatase type 2A regulator activityIEA-
GO:0008601protein phosphatase type 2A regulator activityNAS10945473 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionIEA-
GO:0007165signal transductionNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000159protein phosphatase type 2A complexIEA-
GO:0000159protein phosphatase type 2A complexNAS10945473 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARL2ARFL2ADP-ribosylation factor-like 2-HPRD,BioGRID12912990 
CCT299D8.1 | CCT-beta | CCTB | MGC142074 | MGC142076 | PRO1633 | TCP-1-betachaperonin containing TCP1, subunit 2 (beta)Affinity Capture-MSBioGRID18782753 
CCT3CCT-gamma | CCTG | PIG48 | TCP-1-gamma | TRIC5chaperonin containing TCP1, subunit 3 (gamma)Affinity Capture-MSBioGRID18782753 
CCT4CCT-DELTA | Cctd | MGC126164 | MGC126165 | SRBchaperonin containing TCP1, subunit 4 (delta)Affinity Capture-MSBioGRID18782753 
CCT5CCT-epsilon | CCTE | KIAA0098 | TCP-1-epsilonchaperonin containing TCP1, subunit 5 (epsilon)Affinity Capture-MSBioGRID18782753 
CCT6ACCT-zeta | CCT-zeta-1 | CCT6 | Cctz | HTR3 | MGC126214 | MGC126215 | MoDP-2 | TCP-1-zeta | TCP20 | TCPZ | TTCP20chaperonin containing TCP1, subunit 6A (zeta 1)Affinity Capture-MSBioGRID18782753 
CCT7CCT-ETA | Ccth | MGC110985 | Nip7-1 | TCP-1-etachaperonin containing TCP1, subunit 7 (eta)Affinity Capture-MSBioGRID18782753 
CCT8C21orf112 | Cctq | D21S246 | KIAA0002 | PRED71chaperonin containing TCP1, subunit 8 (theta)Affinity Capture-MSBioGRID18782753 
PPP2CAPP2Ac | PP2CA | RP-Cprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoformAffinity Capture-MSBioGRID18782753 
PPP2R1AMGC786 | PR65Aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoformAffinity Capture-MSBioGRID18782753 
PPP2R1BMGC26454 | PR65Bprotein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoformAffinity Capture-MSBioGRID18782753 
RAF1CRAF | NS5 | Raf-1 | c-Rafv-raf-1 murine leukemia viral oncogene homolog 1RAF1 (c-Raf) interacts with an unspecified isoform of PPP2R2C (PP2A-C).BIND16041367 
TCP1CCT-alpha | CCT1 | CCTa | D6S230E | TCP-1-alphat-complex 1Affinity Capture-MSBioGRID18782753 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_TIGHT_JUNCTION 13486All SZGR genes in this pathway
BIOCARTA_CHREBP2_PATHWAY 4235All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP 380215All SZGR genes in this pathway
WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN 10166All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
PEREZ_TP53_AND_TP63_TARGETS 205145All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN 11064All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_DN 411249All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP 195138All SZGR genes in this pathway
SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN 8151All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
FUJII_YBX1_TARGETS_DN 202132All SZGR genes in this pathway
HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP 3624All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN 264159All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_UP 266142All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-194270827141Ahsa-miR-194UGUAACAGCAACUCCAUGUGGA
miR-200bc/429187018771A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-218173617431A,m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-32026832689m8hsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-369-3p187218791A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-37418731879m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-493-5p18791885m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-505265326591Ahsa-miR-505GUCAACACUUGCUGGUUUCCUC
miR-543270627121Ahsa-miR-543AAACAUUCGCGGUGCACUUCU
hsa-miR-543AAACAUUCGCGGUGCACUUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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