Gene Page: LRRC1

Summary
GeneID  55227
Symbol  LRRC1
Synonyms  FLJ10775|FLJ11834|LANO|dJ523E19.1
Description  leucine rich repeat containing 1
See related  HGNC:14307|MIM:608195|Ensembl:ENSG00000137269|
Locus tag  -
Gene type  protein-coding
Map location  6p12.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RBM140.930.90
CCDC710.930.94
PCIF10.930.92
ZNF5740.920.89
USP210.920.91
TOR2A0.920.91
SMPD40.910.89
DCAKD0.910.89
FAM127C0.910.88
RSAD10.910.89
Top 10 negatively co-expressed genes
AF347015.27-0.69-0.82
AF347015.31-0.69-0.81
MT-CO2-0.67-0.80
AF347015.8-0.66-0.81
MT-CYB-0.66-0.80
AF347015.33-0.65-0.77
C5orf53-0.64-0.69
AF347015.15-0.63-0.79
AF347015.21-0.63-0.85
AF347015.2-0.60-0.77
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CRMP1DPYSL1 | DRP-1 | DRP1collapsin response mediator protein 1Two-hybridBioGRID16169070 
DLG1DKFZp761P0818 | DKFZp781B0426 | DLGH1 | SAP97 | dJ1061C18.1.1 | hdlgdiscs, large homolog 1 (Drosophila)Two-hybridBioGRID11440998 
DLG4FLJ97752 | FLJ98574 | PSD95 | SAP90discs, large homolog 4 (Drosophila)-HPRD,BioGRID11440998 
ERBB2IPERBIN | LAP2erbb2 interacting protein-HPRD,BioGRID11440998 
KIAA1377-KIAA1377Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_UP 306188All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN 275168All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_DN 232139All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN 284156All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP 178108All SZGR genes in this pathway
LOPEZ_EPITHELIOID_MESOTHELIOMA 1711All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_UP 207143All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN 505328All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.1595601m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5065946011A,m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-13412551261m8hsa-miR-134brainUGUGACUGGUUGACCAGAGGG
miR-142-3p245251m8hsa-miR-142-3pUGUAGUGUUUCCUACUUUAUGGA
miR-22434440m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-3814644701Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-4955025081Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
miR-5449199251Ahsa-miR-544AUUCUGCAUUUUUAGCAAGU
miR-9794800m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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