Gene Page: AMBRA1

Summary
GeneID  55626
Symbol  AMBRA1
Synonyms  FLJ20294|KIAA1736|MGC33725|WDR94
Description  autophagy/beclin-1 regulator 1
See related  HGNC:25990|MIM:611359|Ensembl:ENSG00000110497|HPRD:10975|
Locus tag  -
Gene type  protein-coding
Map location  11p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DNAJC120.660.72
VWA5A0.650.71
ADK0.650.70
SCOC0.640.68
MAOA0.630.65
BCHE0.630.60
PDHB0.630.68
CCNE10.630.67
SCP20.630.65
PAM0.630.70
Top 10 negatively co-expressed genes
SCUBE1-0.47-0.39
SATB2-0.45-0.28
NHSL1-0.45-0.28
SLA-0.44-0.17
TTC28-0.43-0.21
WDR86-0.42-0.41
MPPED1-0.42-0.26
ADRA2A-0.42-0.22
GJC1-0.41-0.25
NAV2-0.41-0.21
Gene Ontology
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentIEAneurite (GO term level: 5)-
GO:0006914autophagyIEA-
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIDA17589504 
GO:0031410cytoplasmic vesicleIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_DN 185115All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_DN 165107All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_DN 180110All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN 181107All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
CHUNG_BLISTER_CYTOTOXICITY_UP 13484All SZGR genes in this pathway
MIZUSHIMA_AUTOPHAGOSOME_FORMATION 1915All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-200bc/4297397461A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-23914920m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-3239149201Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-485-3p9079131Ahsa-miR-485-3pGUCAUACACGGCUCUCCUCUCU
miR-73503571A,m8hsa-miR-7SZUGGAAGACUAGUGAUUUUGUUG
miR-999910061A,m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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