Gene Page: CCDC88A

Summary
GeneID  55704
Symbol  CCDC88A
Synonyms  APE|DKFZp686D0630|GIRDIN|GIV|GRDN|HkRP1|KIAA1212
Description  coiled-coil domain containing 88A
See related  HGNC:25523|MIM:609736|Ensembl:ENSG00000115355|HPRD:10051|HPRD:11131|
Locus tag  -
Gene type  protein-coding
Map location  2p16.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.1667 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HDAC30.950.94
BAT10.940.93
FANCG0.930.90
DAXX0.930.93
ZNF70.920.92
FAM48A0.920.91
VPS16A0.920.93
ZSCAN210.920.90
USF10.920.94
SSRP10.920.91
Top 10 negatively co-expressed genes
AF347015.27-0.79-0.90
AF347015.31-0.78-0.88
MT-CO2-0.77-0.88
AF347015.33-0.76-0.86
MT-CYB-0.76-0.87
AF347015.8-0.75-0.88
AIFM3-0.74-0.77
AF347015.15-0.74-0.87
HLA-F-0.73-0.74
AF347015.2-0.72-0.88
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIDA16139227 
GO:0008017microtubule bindingISS-
GO:0042803protein homodimerization activityIPI16139227 
GO:0035091phosphoinositide bindingIDA16139227 
GO:0043422protein kinase B bindingIPI16139227 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001932regulation of protein amino acid phosphorylationISS-
GO:0016044membrane organizationIDA15882442 
GO:0006275regulation of DNA replicationISS-
GO:0016477cell migrationIMP16139227 
GO:0042127regulation of cell proliferationISS-
GO:0032956regulation of actin cytoskeleton organizationIMP16139227 
GO:0032148activation of protein kinase B activityISS-
GO:0030032lamellipodium biogenesisIMP16139227 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIDA15882442 
GO:0005829cytosolIDA15749703 
GO:0005737cytoplasmIEA-
GO:0005783endoplasmic reticulumIDA15882442 
GO:0030027lamellipodiumIDA16139227 
GO:0005886plasma membraneIDA15882442 
GO:0031410cytoplasmic vesicleIDA15882442 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP 175120All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL 330217All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP 7856All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_DN 5739All SZGR genes in this pathway
TSENG_IRS1_TARGETS_DN 13588All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
BURTON_ADIPOGENESIS_11 5740All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN 264168All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN 4026All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_D_DN 7834All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_DN 185116All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP 288168All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_PCA3_DN 6938All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN 5639All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2_M 216124All SZGR genes in this pathway
BILANGES_SERUM_SENSITIVE_VIA_TSC2 3925All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN 180116All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_B 517302All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101273627421Ahsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-12826462652m8hsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-129-5p108110871Ahsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-130/30129862992m8hsa-miR-130abrainCAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrainCAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3pUAGUGCAAUAUUGCUUAUAGGGUUU
miR-144273527421A,m8hsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-1826052611m8hsa-miR-18aUAAGGUGCAUCUAGUGCAGAUA
hsa-miR-18bUAAGGUGCAUCUAGUGCAGUUA
miR-1814794851Ahsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-1822192251Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-19192419311A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-203.131233129m8hsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-218107610831A,m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-378271827251A,m8hsa-miR-378CUCCUGACUCCAGGUCCUGUGU
miR-43188941Ahsa-miR-431UGUCUUGCAGGCCGUCAUGCA
miR-488274727531Ahsa-miR-488CCCAGAUAAUGGCACUCUCAA
miR-495105110571Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
miR-53955611Ahsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
miR-93.hd/291-3p/294/295/302/372/373/520298829941Ahsa-miR-93brainAAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302aUAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302bUAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302cUAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302dUAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520eAAAGUGCUUCCUUUUUGAGGG
hsa-miR-520aAAAGUGCUUCCCUUUGGACUGU
hsa-miR-520bAAAGUGCUUCCUUUUAGAGGG
hsa-miR-520cAAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520dAAAGUGCUUCUCUUUGGUGGGUU
miR-962192251Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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