Gene Page: PROP1

Summary
GeneID  5626
Symbol  PROP1
Synonyms  -
Description  PROP paired-like homeobox 1
See related  HGNC:9455|MIM:601538|Ensembl:ENSG00000175325|HPRD:03325|
Locus tag  -
Gene type  protein-coding
Map location  5q35.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.0276 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003682chromatin bindingIEA-
GO:0003700transcription factor activityIEA-
GO:0003702RNA polymerase II transcription factor activityTAS9462743 
GO:0008022protein C-terminus bindingIEA-
GO:0008013beta-catenin bindingIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007417central nervous system developmentTASBrain (GO term level: 6)9462743 
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA-
GO:0001568blood vessel developmentIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0009953dorsal/ventral pattern formationIEA-
GO:0009887organ morphogenesisIEA-
GO:0043066negative regulation of apoptosisIEA-
GO:0021979hypothalamus cell differentiationIEA-
GO:0048732gland developmentIEA-
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA-
GO:0048850hypophysis morphogenesisIEA-
GO:0060126somatotropin secreting cell differentiationIEA-
GO:0060070Wnt receptor signaling pathway through beta-cateninIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005667transcription factor complexIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
HESX1ANF | MGC138294 | RPXHESX homeobox 1-HPRD11283314 
PITX2ARP1 | Brx1 | IDG2 | IGDS | IGDS2 | IHG2 | IRID2 | MGC111022 | MGC20144 | Otlx2 | PTX2 | RGS | RIEG | RIEG1 | RSpaired-like homeodomain 2-HPRD9685346 
 
Pathway annotation


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