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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: EIF4ENIF1

Summary

GeneID

56478

Symbol

EIF4ENIF1

Synonyms

4E-T|Clast4|FLJ21601|FLJ26551

Description

eukaryotic translation initiation factor 4E nuclear import factor 1

Locus tag

Gene type

protein-coding

Map location

22q11.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.031

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0033

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

ABCB1

0.74

0.71

GBP3

0.73

0.68

APOL3

0.72

0.69

ABCG2

0.71

0.65

EPAS1

0.69

TGFBR2

0.69

0.63

GBP4

0.68

0.71

TGM2

0.68

0.63

APOL1

0.67

0.66

GPR116

0.67

Top 10 negatively co-expressed genes

MED19

-0.53

-0.57

ALKBH2

-0.52

-0.58

C17orf48

-0.51

-0.54

NR2C2AP

-0.51

-0.54

RPL10A

-0.51

-0.61

ZNF821

-0.50

-0.49

POLB

-0.50

-0.55

RPL4

-0.50

-0.54

RPL5

-0.50

-0.60

RBM3

-0.50

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

10856257

GO:0008565

protein transporter activity

TAS

10856257

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0015031

protein transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

IEA

GO:0005634

nucleus

TAS

10856257

GO:0005737

cytoplasm

TAS

10856257

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
EIF4E	CBP \| EIF4E1 \| EIF4EL1 \| EIF4F \| MGC111573	eukaryotic translation initiation factor 4E	-	HPRD,BioGRID	10856257
EIF4E2	4E-LP \| 4EHP \| EIF4EL3 \| IF4e	eukaryotic translation initiation factor 4E family member 2	Two-hybrid	BioGRID	16189514
SMAD3	DKFZp586N0721 \| DKFZp686J10186 \| HSPC193 \| HsT17436 \| JV15-2 \| MADH3 \| MGC60396	SMAD family member 3	Smad3 interacts with 4-ET. This interaction was modeled on a demonstrated interaction between human Smad3 and mouse 4-ET.	BIND	14651998

Pathway annotation

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-23	252	258	1A	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	252	258	1A	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-377	502	509	1A,m8	hsa-miR-377	AUCACACAAAGGCAACUUUUGU
miR-493-5p	327	333	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.