Gene Page

Gene Page: ARHGAP20

Summary

GeneID

57569

Symbol

ARHGAP20

Synonyms

KIAA1391|RARHOGAP

Description

Rho GTPase activating protein 20

Locus tag

Gene type

protein-coding

Map location

11q22.3-q23.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.006

Expression

P value: 1.474

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005096

GTPase activator activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007165

signal transduction

IEA

GO:0045786

negative regulation of cell cycle

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
REACTOME_SIGNALING_BY_RHO_GTPASES	113	81	All SZGR genes in this pathway
WANG_RESPONSE_TO_BEXAROTENE_DN	29	19	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP	487	286	All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS	1038	678	All SZGR genes in this pathway
BENPORATH_EED_TARGETS	1062	725	All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3	1118	744	All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS	652	441	All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN	517	309	All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P7	90	52	All SZGR genes in this pathway
OUILLETTE_CLL_13Q14_DELETION_UP	74	40	All SZGR genes in this pathway
LIN_NPAS4_TARGETS_UP	163	100	All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN	882	538	All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN	244	157	All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP	489	314	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	1583	1589	m8	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-148/152	2256	2262	1A	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-15/16/195/424/497	2222	2229	1A,m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-200bc/429	1561	1568	1A,m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-23	2016	2023	1A,m8	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
				hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
				hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
				hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-323	2015	2022	1A,m8	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-381	2148	2154	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-485-3p	2056	2062	m8	hsa-miR-485-3p	GUCAUACACGGCUCUCCUCUCU
miR-503	2223	2229	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG
miR-544	2213	2220	1A,m8	hsa-miR-544	AUUCUGCAUUUUUAGCAAGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.