Gene Page

Gene Page: BEGAIN

Summary

GeneID

57596

Symbol

BEGAIN

Synonyms

KIAA1446

Description

brain-enriched guanylate kinase-associated homolog (rat)

Locus tag

Gene type

protein-coding

Map location

14q32.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0119

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

16189514

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005794

Golgi apparatus

IDA

18029348

GO:0005634

nucleus

IDA

18029348

GO:0005737

cytoplasm

IEA

GO:0016020

membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ABLIM1	ABLIM \| DKFZp781D0148 \| FLJ14564 \| KIAA0059 \| LIMAB1 \| LIMATIN \| MGC1224	actin binding LIM protein 1	Two-hybrid	BioGRID	16189514
BAHD1	KIAA0945	bromo adjacent homology domain containing 1	Two-hybrid	BioGRID	16189514
BEGAIN	KIAA1446	brain-enriched guanylate kinase-associated homolog (rat)	-	HPRD,BioGRID	12097487
C16orf48	DAKV6410 \| DKFZp434A1319	chromosome 16 open reading frame 48	Two-hybrid	BioGRID	16189514
C17orf28	DMC1 \| FLJ43526	chromosome 17 open reading frame 28	Two-hybrid	BioGRID	16189514
CATSPER1	CATSPER \| MGC33335 \| MGC33368	cation channel, sperm associated 1	Two-hybrid	BioGRID	16189514
DEF6	IBP \| SLAT	differentially expressed in FDCP 6 homolog (mouse)	Two-hybrid	BioGRID	16189514
DLG1	DKFZp761P0818 \| DKFZp781B0426 \| DLGH1 \| SAP97 \| dJ1061C18.1.1 \| hdlg	discs, large homolog 1 (Drosophila)	-	HPRD	9756850
DLG4	FLJ97752 \| FLJ98574 \| PSD95 \| SAP90	discs, large homolog 4 (Drosophila)	-	HPRD	9756850
DTNB	MGC17163 \| MGC57126	dystrobrevin, beta	Two-hybrid	BioGRID	16189514
FAM107A	DRR1 \| FLJ30158 \| FLJ45473 \| TU3A	family with sequence similarity 107, member A	Two-hybrid	BioGRID	16189514
HGS	HRS \| ZFYVE8	hepatocyte growth factor-regulated tyrosine kinase substrate	Two-hybrid	BioGRID	16189514
KIAA0408	FLJ43995 \| RP3-403A15.2	KIAA0408	Two-hybrid	BioGRID	16189514
RBL1	CP107 \| MGC40006 \| PRB1 \| p107	retinoblastoma-like 1 (p107)	Affinity Capture-Western Two-hybrid	BioGRID	16189514
RIBC2	C22orf11	RIB43A domain with coiled-coils 2	Two-hybrid	BioGRID	16189514
TRIM27	RFP \| RNF76	tripartite motif-containing 27	Two-hybrid	BioGRID	16189514
USP2	UBP41 \| USP9	ubiquitin specific peptidase 2	Two-hybrid	BioGRID	16189514
ZFP64	MGC940 \| ZNF338	zinc finger protein 64 homolog (mouse)	Two-hybrid	BioGRID	16189514
ZNF250	FLJ57354 \| MGC111123 \| MGC9718 \| ZFP647 \| ZNF647	zinc finger protein 250	Two-hybrid	BioGRID	16189514
ZNF417	MGC34079	zinc finger protein 417	Two-hybrid	BioGRID	16189514

Pathway annotation

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	695	702	1A,m8	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.