Gene Page

Gene Page: MYOZ1

Summary

GeneID

58529

Symbol

MYOZ1

Synonyms

CS-2|FATZ|MYOZ

Description

myozenin 1

Locus tag

Gene type

protein-coding

Map location

10q22.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

MORF4L2

0.86

0.80

PPHLN1

0.85

0.78

PSMD7

0.84

0.78

EBNA1BP2

0.84

0.80

TBPL1

0.84

0.78

DNAJA2

0.83

0.79

FKBP3

0.83

0.80

PSMC6

0.83

0.82

STRAP

0.83

0.76

SMYD3

0.83

0.78

Top 10 negatively co-expressed genes

AF347015.2

-0.70

-0.53

AF347015.8

-0.68

-0.52

AF347015.26

-0.68

-0.52

AF347015.15

-0.67

-0.53

MT-CYB

-0.66

-0.52

MT-CO2

-0.66

-0.49

AF347015.33

-0.66

-0.52

AF347015.18

-0.64

-0.50

AF347015.31

-0.62

-0.49

AF347015.21

-0.62

-0.41

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

10427098 |10984498 |11114196
|11171996 |11842093
|16076904

GO:0005198

structural molecule activity

IEA

GO:0051373

FATZ binding

IDA

10984498

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0030239

myofibril assembly

TAS

11114196

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0042995

cell projection

IEA

axon (GO term level: 4)

GO:0005634

nucleus

IEA

GO:0015629

actin cytoskeleton

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACTN1	FLJ40884	actinin, alpha 1	-	HPRD	11842093
ACTN1	FLJ40884	actinin, alpha 1	Two-hybrid	BioGRID	16189514
ACTN2	CMD1AA	actinin, alpha 2	FATZ interacts with ACTN2.	BIND	10984498
ACTN2	CMD1AA	actinin, alpha 2	-	HPRD,BioGRID	10984498
ACTN4	ACTININ-4 \| DKFZp686K23158 \| FSGS \| FSGS1	actinin, alpha 4	Two-hybrid	BioGRID	16189514
FLNC	ABP-280 \| ABP280A \| ABPA \| ABPL \| FLJ10186 \| FLN2	filamin C, gamma (actin binding protein 280)	FATZ interacts with FLNC.	BIND	10984498
			-	HPRD,BioGRID	10984498 \|11171996
			Calsarcin-2 interacts with gamma-filamin.	BIND	11842093
LDB3	CYPHER \| FLJ35865 \| KIAA01613 \| KIAA0613 \| ORACLE \| PDLIM6 \| ZASP \| ldb3z1 \| ldb3z4	LIM domain binding 3	ZASP/Cypher-2 interacts with Calsarcin-2.	BIND	11842093
LDB3		LIM domain binding 3	ZASP/Cypher-1 interacts with Calsarcin-2. This interaction was modeled on a demonstrated interaction between mouse ZASP/Cypher-1 and human Calsarcin-2.	BIND	11842093
MAGEA11	MAGE-11 \| MAGE11 \| MAGEA-11 \| MGC10511	melanoma antigen family A, 11	Two-hybrid	BioGRID	16189514
PNKP	PNK	polynucleotide kinase 3'-phosphatase	Two-hybrid	BioGRID	16189514
PPP3CA	CALN \| CALNA \| CALNA1 \| CCN1 \| CNA1 \| PPP2B	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	Affinity Capture-Western	BioGRID	11114196
TCAP	CMD1N \| LGMD2G \| T-cap \| TELE \| telethonin	titin-cap (telethonin)	FATZ interacts with TELE.	BIND	10984498
TCAP	CMD1N \| LGMD2G \| T-cap \| TELE \| telethonin	titin-cap (telethonin)	-	HPRD,BioGRID	10984498

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-136	104	110	m8	hsa-miR-136	ACUCCAUUUGUUUUGAUGAUGGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.