Gene Page: RALB

Summary
GeneID  5899
Symbol  RALB
Synonyms  -
Description  v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)
See related  HGNC:9840|MIM:179551|Ensembl:ENSG00000144118|HPRD:01550|
Locus tag  -
Gene type  protein-coding
Map location  2cen-q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.023 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00755 
ExpressionExpressionP value: 1.457 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
VPS450.860.85
SMU10.850.82
C15orf440.840.81
ANAPC70.840.81
ALDH3A20.840.81
MBIP0.830.82
CNBP0.830.79
EIF2AK10.830.76
SNX20.830.79
ZC3H140.820.79
Top 10 negatively co-expressed genes
AF347015.21-0.75-0.63
MT-CO2-0.73-0.66
AF347015.8-0.71-0.65
AF347015.31-0.70-0.65
MT-CYB-0.69-0.63
AF347015.2-0.68-0.63
IFI27-0.67-0.64
AF347015.27-0.67-0.63
AF347015.15-0.66-0.64
AF347015.33-0.66-0.60
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIPI7673236 
GO:0005525GTP bindingIEA-
GO:0005525GTP bindingTAS2120779 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007265Ras protein signal transductionEXP11520933 
GO:0007264small GTPase mediated signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005886plasma membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EXOC2FLJ11026 | SEC5 | SEC5L1 | Sec5pexocyst complex component 2Two-hybridBioGRID14525976 
EXOC8EXO84 | Exo84p | SEC84exocyst complex component 8Affinity Capture-Western
Two-hybrid		BioGRID14525976 
RALBP1RIP1 | RLIP1 | RLIP76ralA binding protein 1-HPRD,BioGRID7673236 
RalB interacts with RLIP76.BIND7673236 
REPS2POB1RALBP1 associated Eps domain containing 2-HPRD9422736 
RGL4MGC119678 | MGC119680 | Rgrral guanine nucleotide dissociation stimulator-like 4-HPRD,BioGRID12874025 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_PANCREATIC_CANCER 7056All SZGR genes in this pathway
PID_P38_ALPHA_BETA_PATHWAY 3125All SZGR genes in this pathway
PID_CXCR4_PATHWAY 10278All SZGR genes in this pathway
PID_FOXO_PATHWAY 4943All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_SIGNALLING_TO_RAS 2723All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 137105All SZGR genes in this pathway
REACTOME_SIGNALLING_TO_ERKS 3630All SZGR genes in this pathway
REACTOME_P38MAPK_EVENTS 1312All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
WANG_BARRETTS_ESOPHAGUS_UP 5127All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
ALCALA_APOPTOSIS 8860All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
LEE_LIVER_CANCER_MYC_UP 5430All SZGR genes in this pathway
LEE_LIVER_CANCER_MYC_TGFA_UP 6140All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_SCC_UP 12375All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN 264168All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_UP 2515All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-203.1128012871A,m8hsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-9140314091Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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