Gene Page: RASGRF1

Summary
GeneID  5923
Symbol  RASGRF1
Synonyms  CDC25|CDC25L|GNRP|GRF1|GRF55|H-GRF55|PP13187
Description  Ras protein-specific guanine nucleotide-releasing factor 1
See related  HGNC:9875|MIM:606600|Ensembl:ENSG00000058335|
Locus tag  -
Gene type  protein-coding
Map location  15q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 5 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PAIP20.860.87
MORF4L20.850.86
VBP10.840.85
AZI20.840.83
ACP10.840.83
VAPA0.840.83
GFM20.830.86
SCCPDH0.830.81
ORC3L0.830.81
CAPZA10.830.81
Top 10 negatively co-expressed genes
AF347015.2-0.58-0.44
AF347015.18-0.55-0.44
AF347015.26-0.55-0.42
AF347015.8-0.55-0.43
MT-CO2-0.54-0.41
AF347015.15-0.53-0.42
MT-CYB-0.53-0.42
AF347015.33-0.52-0.43
AF347015.21-0.51-0.33
AF347015.31-0.49-0.40
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0035254glutamate receptor bindingIEAglutamate (GO term level: 5)-
GO:0005089Rho guanyl-nucleotide exchange factor activityIEA-
GO:0005085guanyl-nucleotide exchange factor activityIEA-
GO:0005515protein bindingISS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0031175neurite developmentISSneuron, axon, neurite, dendrite (GO term level: 10)-
GO:0048168regulation of neuronal synaptic plasticityIEAneuron, Synap (GO term level: 9)-
GO:0008283cell proliferationIEA-
GO:0007616long-term memoryNAS10918068 
GO:0035020regulation of Rac protein signal transductionISS-
GO:0035023regulation of Rho protein signal transductionIEA-
GO:0051056regulation of small GTPase mediated signal transductionIEA-
GO:0032320positive regulation of Ras GTPase activityISS-
GO:0032863activation of Rac GTPase activityISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0019717synaptosomeNASSynap, Brain (GO term level: 7)10918068 
GO:0030426growth coneISSaxon, dendrite (GO term level: 5)-
GO:0005829cytosolISS-
GO:0005622intracellularIEA-
GO:0005886plasma membraneNAS10918068 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
HRASC-BAS/HAS | C-H-RAS | C-HA-RAS1 | CTLO | H-RASIDX | HAMSV | HRAS1 | K-RAS | N-RAS | RASH1v-Ha-ras Harvey rat sarcoma viral oncogene homologTwo-hybridBioGRID9154803 
MARK3CTAK1 | KP78 | PAR1AMAP/microtubule affinity-regulating kinase 3Affinity Capture-Western
Reconstituted Complex
BioGRID9543386 
PPP1R9BFLJ30345 | PPP1R6 | PPP1R9 | SPINO | Spnprotein phosphatase 1, regulatory (inhibitor) subunit 9BAffinity Capture-WesternBioGRID12531897 
TNK2ACK | ACK1 | FLJ44758 | FLJ45547 | p21cdc42Hstyrosine kinase, non-receptor, 2-HPRD10882715 
USP8FLJ34456 | HumORF8 | KIAA0055 | MGC129718 | UBPYubiquitin specific peptidase 8-HPRD11500497 
YWHABGW128 | HS1 | KCIP-1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptideReconstituted ComplexBioGRID9543386 
YWHAE14-3-3E | FLJ45465 | KCIP-1 | MDCR | MDStyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide-HPRD11533041 
 


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