|
GeneID |
610
|
Symbol |
HCN2
|
Synonyms |
BCNG-2|BCNG2|HAC-1
|
Description |
hyperpolarization activated cyclic nucleotide-gated potassium channel 2 |
See related |
HGNC:4846|MIM:602781|Ensembl:ENSG00000099822|HPRD:07213| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
19p13.3 |
|
|
|
Gene set name |
Method of gene set |
Evidence |
Info |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail |
|
|
General Gene Expression (microarray) ? |
|
|
|
Gene Expression in Brain Regions (new) |
|
|
Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
FAM171A1 | 0.89 | 0.88 | | |
ULK1 | 0.87 | 0.89 | | |
SRF | 0.85 | 0.91 | | |
AKAP1 | 0.84 | 0.86 | | |
MESDC1 | 0.83 | 0.84 | | |
RAPGEF1 | 0.83 | 0.89 | | |
WDTC1 | 0.82 | 0.88 | | |
RUNDC1 | 0.82 | 0.86 | | |
DAB2IP | 0.82 | 0.88 | | |
FAM168B | 0.82 | 0.87 | | |
Top 10 negatively co-expressed genes | AF347015.21 | -0.68 | -0.76 | | |
AF347015.31 | -0.63 | -0.67 | | |
MT-CO2 | -0.62 | -0.66 | | |
C1orf54 | -0.62 | -0.74 | | |
GNG11 | -0.60 | -0.67 | | |
SYCP3 | -0.60 | -0.68 | | |
AF347015.8 | -0.59 | -0.64 | | |
HIGD1B | -0.58 | -0.65 | | |
NOSTRIN | -0.58 | -0.63 | | |
MYL3 | -0.57 | -0.62 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0000166 | nucleotide binding | IEA | | - |
GO:0005515 | protein binding | IEA | | - |
GO:0005244 | voltage-gated ion channel activity | IEA | | - |
GO:0005249 | voltage-gated potassium channel activity | IEA | | - |
GO:0005272 | sodium channel activity | IEA | | - |
GO:0030552 | cAMP binding | IEA | | - |
GO:0030955 | potassium ion binding | IEA | | - |
GO:0031402 | sodium ion binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0007267 | cell-cell signaling | TAS | | 9630217 |
GO:0006814 | sodium ion transport | IEA | | - |
GO:0006812 | cation transport | TAS | | 10228147 |
GO:0006813 | potassium ion transport | IEA | | - |
GO:0006936 | muscle contraction | TAS | | 10228147 |
GO:0042391 | regulation of membrane potential | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0016020 | membrane | IEA | | - |
GO:0016021 | integral to membrane | IEA | | - |
GO:0008076 | voltage-gated potassium channel complex | TAS | | 9630217 |
|
|
|
|
|
|
|
|
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
|