Gene Page: RPL5

Summary
GeneID  6125
Symbol  RPL5
Synonyms  MGC117339|MSTP030
Description  ribosomal protein L5
See related  HGNC:10360|MIM:603634|Ensembl:ENSG00000122406|HPRD:04699|
Locus tag  -
Gene type  protein-coding
Map location  1p22.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0064 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RPS25P80.960.96
RPL380.960.94
RPL37A0.960.95
RPS240.950.94
RPS80.950.95
RPL230.940.94
RPS27A0.940.90
RPL260.940.91
RPL300.940.94
RPS230.940.93
Top 10 negatively co-expressed genes
ATP10A-0.61-0.79
BCL2L2-0.59-0.82
SYNM-0.57-0.79
MAP3K5-0.57-0.75
PTPRB-0.57-0.74
ACSL6-0.57-0.76
EPB41L2-0.57-0.76
LDHD-0.56-0.71
VWA5B2-0.56-0.78
PK4P-0.56-0.70
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003735structural constituent of ribosomeIEA-
GO:0003735structural constituent of ribosomeTAS7772601 
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI9465063 |12054647 
GO:00080975S rRNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006414translational elongationEXP15189156 
GO:0006412translationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP14567916 
GO:0005840ribosomeIEA-
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
GO:0022625cytosolic large ribosomal subunitTAS7772601 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CSNK2A1CK2A1 | CKIIcasein kinase 2, alpha 1 polypeptide-HPRD,BioGRID10491318 
CSNK2BCK2B | CK2N | CSK2B | G5A | MGC138222 | MGC138224casein kinase 2, beta polypeptide-HPRD8806611 |9042965 
|9738462 |10491318 
Two-hybridBioGRID8806611 |9042965 
|11710515 |14667819 
EIF5AA | EIF-5A | EIF5A1 | MGC104255 | MGC99547 | uORFeukaryotic translation initiation factor 5A-HPRD,BioGRID9465063 
HARSFLJ20491 | HRShistidyl-tRNA synthetase-HPRD,BioGRID8049265 
IPO13IMP13 | KAP13 | KIAA0724 | RANBP13importin 13Reconstituted ComplexBioGRID11447110 
IPO5DKFZp686O1576 | FLJ43041 | IMB3 | KPNB3 | MGC2068 | RANBP5importin 5-HPRD,BioGRID9687515 
IPO7FLJ14581 | Imp7 | MGC138673 | RANBP7importin 7-HPRD,BioGRID9687515 
MDM2HDMX | MGC71221 | hdm2Mdm2 p53 binding protein homolog (mouse)-HPRD,BioGRID7935455 |14612427 
PDCD4H731 | MGC33046 | MGC33047programmed cell death 4 (neoplastic transformation inhibitor)-HPRD,BioGRID12054647 
RPL5MGC117339 | MSTP030ribosomal protein L5Protein-RNA
Two-hybrid		BioGRID10491318 |15231747 
TNPO1IPO2 | KPNB2 | MIP | MIP1 | TRNtransportin 1-HPRD,BioGRID9687515 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_RIBOSOME 8843All SZGR genes in this pathway
PID_P53_REGULATION_PATHWAY 5950All SZGR genes in this pathway
REACTOME_TRANSLATION 22275All SZGR genes in this pathway
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 17953All SZGR genes in this pathway
REACTOME_PEPTIDE_CHAIN_ELONGATION 15341All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 17651All SZGR genes in this pathway
REACTOME_METABOLISM_OF_MRNA 284128All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA 330155All SZGR genes in this pathway
REACTOME_INFLUENZA_LIFE_CYCLE 20372All SZGR genes in this pathway
REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 16947All SZGR genes in this pathway
REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 17657All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_UP 5534All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_DN 214133All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP 271175All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP 201127All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_HIF1A_UP 7749All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP 236139All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
LU_IL4_SIGNALING 9456All SZGR genes in this pathway
JIANG_AGING_CEREBRAL_CORTEX_UP 3627All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
MODY_HIPPOCAMPUS_PRENATAL 4233All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2 7142All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP 196137All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_UP 5333All SZGR genes in this pathway
IRITANI_MAD1_TARGETS_DN 4730All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_DN 18197All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
DANG_MYC_TARGETS_UP 143100All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB 14583All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_UP 14094All SZGR genes in this pathway
BILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES 6835All SZGR genes in this pathway
KIM_TIAL1_TARGETS 3222All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 403240All SZGR genes in this pathway
BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE 15186All SZGR genes in this pathway
HOLLEMAN_ASPARAGINASE_RESISTANCE_B_ALL_UP 2615All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-3761319m8hsa-miR-376aAUCAUAGAGGAAAAUCCACGU
hsa-miR-376bAUCAUAGAGGAAAAUCCAUGUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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