Gene Page: SELPLG

Summary
GeneID  6404
Symbol  SELPLG
Synonyms  CD162|CLA|PSGL-1|PSGL1
Description  selectin P ligand
See related  HGNC:10722|MIM:600738|Ensembl:ENSG00000110876|HPRD:02845|
Locus tag  -
Gene type  protein-coding
Map location  12q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.684 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CSRP10.790.85
TMBIM10.780.82
CBR10.780.83
CRYAB0.780.89
RTKN0.780.89
TECR0.770.73
MAL0.770.90
HAPLN20.760.87
CMTM50.760.89
CISD30.750.80
Top 10 negatively co-expressed genes
NKIRAS2-0.63-0.73
CRMP1-0.61-0.73
KIAA1949-0.61-0.74
ZNF45-0.60-0.71
HN1-0.60-0.74
TUBB2B-0.60-0.75
TTC27-0.60-0.72
ZNF311-0.59-0.75
PPM1G-0.59-0.70
DNAJC9-0.59-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005102receptor bindingNASNeurotransmitter (GO term level: 4)7505206 
GO:0005529sugar bindingIEA-
GO:0008367bacterial bindingTAS10834846 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionTAS7505206 
GO:0050901leukocyte tethering or rollingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionTAS7505206 
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneTAS7505206 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MSN-moesin-HPRD,BioGRID12115638 
SELECD62E | ELAM | ELAM1 | ESEL | LECAM2selectin E-HPRD8621728 |9128259 
SELPCD62 | CD62P | FLJ45155 | GMP140 | GRMP | LECAM3 | PADGEM | PSELselectin P (granule membrane protein 140kDa, antigen CD62)-HPRD,BioGRID9128259 |10713099 
SELPLGCD162 | CLA | PSGL-1 | PSGL1selectin P ligand-HPRD,BioGRID10713099 
TPST1-tyrosylprotein sulfotransferase 1TPST interacts with PSGL-1. This interaction was modelled on a demonstrated interaction between zebrafish TSPT and human PSGL-1.BIND15060624 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
BIOCARTA_GRANULOCYTES_PATHWAY 149All SZGR genes in this pathway
BIOCARTA_LAIR_PATHWAY 1712All SZGR genes in this pathway
PID_AMB2_NEUTROPHILS_PATHWAY 4132All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
BIDUS_METASTASIS_DN 16193All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
MARKEY_RB1_ACUTE_LOF_UP 215137All SZGR genes in this pathway
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP 5232All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_6 8454All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
LIU_NASOPHARYNGEAL_CARCINOMA 7038All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP 283177All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP 7851All SZGR genes in this pathway
KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP 5129All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP 6348All SZGR genes in this pathway
NADLER_OBESITY_UP 6134All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
HANSON_HRAS_SIGNALING_VIA_NFKB 2214All SZGR genes in this pathway
LINDVALL_IMMORTALIZED_BY_TERT_DN 8056All SZGR genes in this pathway
MOREIRA_RESPONSE_TO_TSA_UP 2823All SZGR genes in this pathway
LEE_AGING_CEREBELLUM_UP 8458All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
LEIN_ASTROCYTE_MARKERS 4235All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G 17196All SZGR genes in this pathway
BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP 4730All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP 13179All SZGR genes in this pathway
PARK_APL_PATHOGENESIS_UP 1411All SZGR genes in this pathway
LEE_DIFFERENTIATING_T_LYMPHOCYTE 200115All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
ZHAN_LATE_DIFFERENTIATION_GENES_UP 3324All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_DN 204114All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP 288168All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
MIKKELSEN_IPS_LCP_WITH_H3K4ME3 174100All SZGR genes in this pathway
MIKKELSEN_ES_LCP_WITH_H3K4ME3 14280All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
HUANG_GATA2_TARGETS_UP 14996All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_UP 266142All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


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